个体化抗血小板治疗的成本-效用分析

M. Abdullaev, B. Kantemirova, E. Chernysheva, A. Romanova
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引用次数: 0

摘要

这篇文章包含了对急性冠脉综合征患者支架植入术后几种双重抗血小板治疗方案的比较药物经济成本-效用分析的结果。计算有和没有事先进行CYP2C19药物遗传学检测的治疗方案的费用。根据分析结果,对急性冠状动脉综合征患者来说,最具成本效益的治疗方案是事先进行药物遗传学检查,并选择抗血小板药物普拉格雷治疗慢代谢和中度代谢(按质量计算,平均平均损失为289,111.00卢布)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COST-UTILITY ANALYSIS OF PERSONALIZED ANTIPLATELET THERAPY
The article contains the results of a comparison pharmacoeconomical cost-utility analysis of several options for dual antiplatelet therapy in patients with acute coronary syndrome after stent implanting. The costs for treatment alternatives with and without prior pharmacogenetic testing for CYP2C19 were calculated. According to the results of the analysis the most cost-effective treatment option for patients with acute coronary syndrome is prior pharmacogenetic testing and the choice of the antiplatelet drug prasugrel in slow and intermediate metabolizers (CUA: 289,111.00 rubles per QALY).
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