[纳洛酮对慢性十二指肠溃疡患者基底、经生长抑素抑制胃分泌的影响]。

Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR Pub Date : 1990-01-01

M Lukin, K Markiewicz

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引用次数: 0

摘要

对13例慢性十二指肠溃疡患者，测定了生长抑素和纳洛酮对胃基本分泌的影响。在静脉滴注生长抑素后，观察到胃基本分泌明显增加。生长抑素还能引起胃液中钠浓度的显著升高和氯浓度的显著降低。总电解质和黏液蛋白分泌随胃液量的变化成比例变化。单次静脉注射纳洛酮不影响生长抑素诱导的胃分泌。慢性十二指肠溃疡患者生长抑素与纳洛酮相互独立影响胃液分泌。

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[Effect of naloxone on basal, by somatostatin inhibited stomach secretion in patients with chronic duodenal ulcer].

In 13 men with chronic duodenal ulcer disease effects of somatostatin and naloxone on basic gastric secretion were determined. Following intravenous somatostatin infusion a significant increase in basic gastric secretion was observed. Somatostatin also induced a significant increase in sodium concentration and a decrease in chloride concentration in the gastric juice. Total electrolyte and mucoprotein secretions changed proportionally to alterations in the gastric juice volume. Somatostatin-induced gastric secretion was unaffected by a single intravenous naloxone administration. In patients with chronic duodenal ulcer disease somatostatin and naloxone affect gastric secretion independently of each other.

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来源期刊

Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR

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