把婴儿淹死在水瓶里。2岁儿童体液供过于求致严重低钠血症1例

Agnieszka Zubkiewicz-Kucharska
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引用次数: 0

摘要

钠在体内的浓度受渗透调节系统控制,渗透调节系统调节水的摄入和排泄。如果该系统失效,血浆钠水平偏离其正常范围(135-145mmol/L),细胞暴露于低渗或高渗应激。低钠血症是最常见的电解质失衡之一,发生在高达20%的住院患者中。定义为血浆钠浓度低于135mmol/L,严重低钠血症低于120mmol/L。低钠血症的症状各不相同,不仅取决于钠的浓度,而且取决于钠血症降低的速度。轻度症状可能包括头痛、认知障碍、嗜睡、恶心和呕吐;然而,这些迹象可能是微妙的,或者可能是无症状的。在严重的低钠血症中,意识障碍、癫痫发作和昏迷是常见的。低钠血症最常见的病因包括呕吐和腹泻、肾上腺功能不全、心、肝和肾功能衰竭、抗利尿激素分泌不当综合征(SIADH)、脑盐消耗综合征、渗透性利尿和高血糖。我们不应该忘记过度水合也是低钠血症的潜在原因。在这里,我们提出一个病例与严重低钠血症的儿童由于液体供应过剩。一名两岁的男孩在持续几分钟的癫痫发作后,因呼吸障碍和意识丧失而被送入急诊科。既往病史无关,精神运动和身体发育正常(体重14kg = 72pc,身高91,5cm = 63pc, BMI 16,7kg/ m2 =75pc)。实验室检查显示钠血症下降120mmol/L,用3%氯化钠逐渐纠正。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
To Drown A Baby in A Water Bottle. Case of A Severe Hyponatremia Caused by Fluid Oversupply in A 2-Year-Old Child
Introduction Sodium concentration in the body is controlled by osmoregulatory system, which regulate water intake and excretion. If this system fails and plasma sodium level stray outside its normal range (135-145mmol/L), the cells are exposed to hypotonic or hypertonic stress. Hyponatremia is one of the most common electrolyte imbalances, occurring in up to 20% of hospitalized patients. It is defined as a plasma sodium concentration lower than 135mmol/L, with severe hyponatremia being below 120mmol/L. The symptoms of hyponatremia vary, depending not only on the concentration of sodium, but also on the rate of lowering of natremia. Mild symptoms may include headaches, cognitive impairment, lethargy, nausea, and vomiting; however, the signs may be subtle, or it may be asymptomatic whatsoever. In severe hyponatremia consciousness disturbances, seizures, and coma are common. The most common cause of hyponatremia include vomiting and diarrhea, adrenal insufficiency, heart, liver and renal failure, syndrome of inappropriate antidiuretic hormone secretion (SIADH), cerebral salt wasting syndrome, osmotic diuresis, and hyperglycemia. One should not forget about overhydration as a potential reason of hyponatremia. Here we present a case of a child with severe hyponatremia due to fluid oversupply. A two-year-old boy was admitted to the Emergency Department after an episode of seizures lasting several minutes, with breathing disorders and loss of consciousness. Past medical history was not relevant, the psychomotor and physical development was normal (body mass 14kg = 72pc, height 91,5cm = 63pc, BMI 16,7kg/m 2 =75pc). Laboratory examination revealed a decreased natremia of 120mmol/L, which was gradually corrected with 3% sodium chloride,
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