非处方药过量致故意死亡:对乙酰氨基酚中毒尸检一例

Milim Kim, Soong-Deok Lee, M. Kim
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引用次数: 0

摘要

对乙酰氨基酚或扑热息痛(n -acetyl- paraaminphenol [APAP])是一种有效的解热和轻度镇痛药物,是世界范围内广泛使用的代表性非处方药。虽然人们普遍认为APAP的使用对公众是安全的,但它可能是致命的,因为意外或故意过量都可能导致肝毒性。2018年,APAP用药过量占美国所有中毒死亡病例的8.8%(276/ 3125)[1]。此外,不仅在美国,在包括英国在内的几个欧洲国家,它也是急性肝衰竭最常见的原因[2]。韩国J腿部医学2020;44:134-139 https://doi.org/10.7580/kjlm.2020.44.3.134
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning
Acetaminophen or paracetamol (N-acetyl-paraaminophenol [APAP]) is an effective antipyretic and mild analgesic drug and is widely used as a representative nonprescription medication worldwide. Although there is a general perception that the use of APAP is safe for the public, it can be fatal as either accidental or intentional overdose can cause hepatotoxicity. APAP overdose accounts for 8.8% (276/3,125) of all cases of fatalities due to poisoning in the United States in 2018 [1]. In addition, it is the most common cause of acute liver failure not only in the United States but also in several European countries, including Great Britain [2]. Korean J Leg Med 2020;44:134-139 https://doi.org/10.7580/kjlm.2020.44.3.134
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