{"title":"非处方药过量致故意死亡:对乙酰氨基酚中毒尸检一例","authors":"Milim Kim, Soong-Deok Lee, M. Kim","doi":"10.7580/kjlm.2020.44.3.134","DOIUrl":null,"url":null,"abstract":"Acetaminophen or paracetamol (N-acetyl-paraaminophenol [APAP]) is an effective antipyretic and mild analgesic drug and is widely used as a representative nonprescription medication worldwide. Although there is a general perception that the use of APAP is safe for the public, it can be fatal as either accidental or intentional overdose can cause hepatotoxicity. APAP overdose accounts for 8.8% (276/3,125) of all cases of fatalities due to poisoning in the United States in 2018 [1]. In addition, it is the most common cause of acute liver failure not only in the United States but also in several European countries, including Great Britain [2]. Korean J Leg Med 2020;44:134-139 https://doi.org/10.7580/kjlm.2020.44.3.134","PeriodicalId":401663,"journal":{"name":"The Korean journal of legal medicine","volume":"44 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2020-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning\",\"authors\":\"Milim Kim, Soong-Deok Lee, M. Kim\",\"doi\":\"10.7580/kjlm.2020.44.3.134\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Acetaminophen or paracetamol (N-acetyl-paraaminophenol [APAP]) is an effective antipyretic and mild analgesic drug and is widely used as a representative nonprescription medication worldwide. Although there is a general perception that the use of APAP is safe for the public, it can be fatal as either accidental or intentional overdose can cause hepatotoxicity. APAP overdose accounts for 8.8% (276/3,125) of all cases of fatalities due to poisoning in the United States in 2018 [1]. In addition, it is the most common cause of acute liver failure not only in the United States but also in several European countries, including Great Britain [2]. Korean J Leg Med 2020;44:134-139 https://doi.org/10.7580/kjlm.2020.44.3.134\",\"PeriodicalId\":401663,\"journal\":{\"name\":\"The Korean journal of legal medicine\",\"volume\":\"44 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-08-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Korean journal of legal medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7580/kjlm.2020.44.3.134\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Korean journal of legal medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7580/kjlm.2020.44.3.134","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning
Acetaminophen or paracetamol (N-acetyl-paraaminophenol [APAP]) is an effective antipyretic and mild analgesic drug and is widely used as a representative nonprescription medication worldwide. Although there is a general perception that the use of APAP is safe for the public, it can be fatal as either accidental or intentional overdose can cause hepatotoxicity. APAP overdose accounts for 8.8% (276/3,125) of all cases of fatalities due to poisoning in the United States in 2018 [1]. In addition, it is the most common cause of acute liver failure not only in the United States but also in several European countries, including Great Britain [2]. Korean J Leg Med 2020;44:134-139 https://doi.org/10.7580/kjlm.2020.44.3.134