K Jung, A Hempel, K D Grützmann, R D Hempel, G Schreiber
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引用次数: 32
摘要
对442例不同年龄(5天至58岁)的随机晨尿样本进行凝胶过滤，测定尿中丙氨酸肽酶、碱性磷酸酶、γ -谷氨酰转移酶和n -乙酰- β - d -氨基葡萄糖苷酶的排泄量。酶排泄与尿肌酐(酶/肌酐比值;U/mmol肌酐)随年龄的增加而显著降低。某些酶排泄在6岁以上年龄组中存在性别差异。从这些调查中，我们计算了5组儿童和青少年以及一组成年人的最高参考区间(97.5百分位数)。
Age-dependent excretion of alanine aminopeptidase, alkaline phosphatase, gamma-glutamyltransferase and N-acetyl-beta-D-glucosaminidase in human urine.
Urinary excretion of alanine aminopeptidase, alkaline phosphatase, gamma-glutamyltransferase and N-acetyl-beta-D-glucosaminidase was determined in gel-filtered samples of morning random urine specimens of 442 subjects of various ages (5 days to 58 years). Enzyme excretion related to urinary creatinine (enzyme/creatinine ratio; U/mmol creatinine) significantly decreased with increasing age. Sex-related differences of some enzyme excretions were found in age groups over 6 years. From these investigations, we calculated upper reference intervals (97.5 percentiles) for 5 age-dependent groups of children and adolescents and for one group of adults.
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