建立疾病的分子分类学

Jisoo Park, Benjamin J. Hescott, D. Slonim
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引用次数: 0

摘要

高通量技术的出现促进了人类疾病分子水平知识的快速增长。然而,现有的疾病分类法倾向于关注疾病的生理特征或医院的组织和计费需求。大多数都没有充分考虑到我们对疾病分子成因的快速增长的知识。更现代的疾病分类大概会建立在临床、生理和分子数据的基础上。在这项研究中,我们分析了仅从分子数据推断疾病关系的能力。这种方法可能为如何最终建立更现代的疾病分类提供见解
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Building a Molecular Taxonomy of Disease
The advent of high throughput technologies contributes to the rapid growth of molecular-level knowledge about human disease. However, existing disease taxonomies tend to focus on either physiological characterizations of disease or the organizational and billing needs of hospitals. Most fail to fully incorporate our rapidly increasing knowledge about molecular causes of disease. More modern disease taxonomies would presumably be built based on the combination of clinical, physiological, and molecular data. In this study, we analyzed our ability to infer disease relationships from molecular data alone. This approach may provide insights into how to ultimately build more modern taxonomies of disease
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