用于高密度ECoG柔性有源电极阵列的85 dB动态范围1.2 mW 156 kS/s生物电位记录IC

S. Ha, Jongkil Park, Y. Chi, J. Viventi, J. Rogers, G. Cauwenberghs
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引用次数: 21

摘要

我们提出了一种低噪声、低功耗的生物电位记录集成电路(IC)的设计、实现和实验表征,该电路支持完全可植入、高密度、主动多路复用和灵活的32×32电极阵列,用于皮质电图(ECoG)神经记录。每个ECoG记录IC包含一个8通道ADC,每个服务一列和多路复用多达32行外部ECoG阵列。每个列ADC通过10位逐次逼近(SA)粗转换信号,并通过7位一阶增量delta-sigma (ΔΣ)转换对残差进行精细转换。SA和ΔΣ级之间的1位重叠支持宽动态范围,瞬时核心范围为3.9 mV,比典型的ECoG信号大得多,同时处理ECoG电极阵列中高达±1 V的电化学和工艺变化。测试表明,在19.5 kS/s和19.4 μA时,在3.3 V / ADC通道下,测量到的动态范围为85 dB, CMRR为87 dB。8通道集成电路占地18mm2,采用0.6 μm 2P3M CMOS。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
85 dB dynamic range 1.2 mW 156 kS/s biopotential recording IC for high-density ECoG flexible active electrode array
We present the design, implementation, and experimental characterization of a low-noise low-power biopotential recording integrated circuit (IC) in support of a fully implantable, high-density, actively multiplexed and flexible 32×32 electrode array for electrocorticography (ECoG) neural recording. Each ECoG recording IC contains an 8-channel ADC, each serving one column and multiplexing up to 32 rows in the external ECoG array. Each column ADC converts signal coarsely by 10-bit successive approximation (SA), and performs fine conversion of the residue by 7-bit 1st order incremental delta-sigma (ΔΣ) conversion. One bit of overlap between SA and ΔΣ stages supports wide dynamic range with an instantaneous core range of 3.9 mV, sufficiently larger than typical ECoG signals, while handling electrochemical and process variations in the ECoG electrode array up to ±1 V. Tests show a measured dynamic range of 85 dB and CMRR of 87 dB at 19.5 kS/s and at 19.4 μA from 3.3 V per ADC channel. The 8-channel IC occupies 18 mm2 in 0.6 μm 2P3M CMOS.
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