Burning mouth syndrome

English) Burning mouth syndrome Burning mouth syndrome (BMS) is characterised by a burning pain in the oral mucosa which persists over time without detectable local or systemic cause. BMS occurs most commonly in women and is usually accompanied by xerostomia and taste disturbances. Several local, systemic and psychological factors have been studied in relation to BMS, but the aetiology remains unclear. Several recent studies suggest that BMS is a neuropathy, although it is not yet clear whether this is a peripheral or central neurogenic dysfunction. Diagnosis of BMS includes exclusion of a wide range of local and systemic causes of oral mucosal burning pain. Treatment options are limited because of the incomplete der er ikke påvist entydige somatiske og/eller psykologiske årsagsforhold som kan forklare de brændende symptomer og deres lokalisation. Imidlertid tyder en række nyere studier på, at BMS er en smertetilstand, hvori indgår neuropatofysiologiske mekanismer. 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The secretion of parotid saliva as stimulated by 10 % citric acid is not related to precipitating factors in burning mouth syndrome. J Oral Pathol Med 2001; 30: 121-4. 20. Chimenos-Küstner E, MarquesSoares MS. Burning mouth and saliva. Med Oral 2002; 7: 244-53. 21. de Moura SA, de Sousa JM, Lima DF, Negreiros AN, Silva Fde V, da Costa LJ. Burning mouth syndrome (BMS): sialometric and sialochemical analysis and salivary protein profile. Gerodontology 2007; 24: 173-6. 22. Pekiner FN, Gümrü B, Demirel GY, Ozbayrak S. Burning mouth syndrome and saliva: detection of salivary trace elements and cytokines. J Oral Pathol Med 2009; 38: 269-75. 23. Lauria G, Majorana A, Borgna M, Lombardi R, Penza P, Padovani A et al. Trigeminal smallfiber sensory neuropathy causes burning mouth syndrome. Pain 2005; 115: 332-7. 24. Jääskeläinen SK, Forssell H, Tenovuo O. Abnormalities of the blink reflex in burning mouth syndrome. Pain 1997; 73: 455-60. 25. Svensson P, Bjerring P, ArendtNielsen L, Kaaber S. Sensory and pain thresholds to orofacial argon laser stimulation in patients with chronic burning mouth syndrome. Clin J Pain 1993; 9: 207-15. 26. Ito M, Kurita K, Ito T, Arao M. Pain threshold and pain recovery after experimental stimu-lation in patients with burning mouth syndrome. Psychiatry Clin Neurosci 2002; 56: 161-8. Litteratur understanding of the etiological mechanisms. Topical clonazepam has been proven effective in some patients with BMS, but may be associated with tolerance and addiction. Early intervention in terms of information about the symptoms and nature of the syndrome seems important for prognosis. Furthermore, psychological interventions including cognitive therapy may be necessary to strengthen the patient’s psychosocial functional level. Interdisciplinary collaboration is essential not only to ensure optimum diagnosis and treatment of BMS, but also to improve our understanding of the etiological mechanisms, and eventually to implement evidence-based treatment. dende smerter primært lokaliseret til tungen, smagsforstyrrelser og xerostomi. Fremadrettet er der behov for interdisciplinært videnskabeligt samarbejde med henblik på at øge indsigten i de ætiologiske og patogenetiske mekanismer og dermed fremme mulighederne for evidensbaserede behandlingsformer.