激素替代疗法和心脏病:最新进展

P. Hannaford
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引用次数: 0

摘要

www.tugsh.com泌尿、妇科和性健康趋势2007年7月/ 8月在本千年之初,据估计,英国50至64岁的妇女中约有三分之一目前在使用激素替代疗法,50%曾经使用过这种疗法的流行,部分是由于观察性研究的证据表明,激素替代疗法使用者对冠心病的保护作用显著,可能达到三分之一然而,这种使用的热情在2003年受到了严重的挫折,当时妇女健康倡议(WHI)的研究人员宣布,他们过早地停止了雌激素与孕激素联合使用的随机试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
HRT and heart disease: an update
www.tugsh.com Trends in Urology Gynaecology & Sexual Health July/August 2007 At the start of this millennium, about a third of women in the UK aged 50–64 years were estimated to be current users of hormone replacement therapy (HRT), and 50 per cent ever-users.1 The popularity of this treatment was driven, in part, by evidence from observational studies suggesting substantial protection from coronary heart disease among HRT users, perhaps by about a third.2 Enthusiasm for such use, however, received a severe setback in 2003 when the Women’s Health Initiative (WHI) investigators announced that they were halting prematurely their randomised trial of oestrogen combined with progestogen.
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