肺癌精准医学:诊断和治疗目的的挑战和机遇

B. Aramini, V. Masciale, F. Banchelli, R. D'amico, M. Dominici, K. Haider
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引用次数: 3

摘要

肺癌是男性和女性癌症死亡的主要原因之一,占所有癌症死亡人数的近25%。精准医学有望改善健康和医疗保健的许多方面,包括测试、药物和其他支持创新的技术,并有可能与广泛专业的科学家建立新的合作伙伴关系。非小细胞肺癌(NSCLC)已成为精准医学治疗实体肿瘤恶性肿瘤成功的一个突出例子。这个过程的第一步涉及新的基于血液的诊断,现在可以无创地提供临床有用的信息。然而,迫切需要鉴定可用于早期诊断的新型生物标志物,特别是用于指导初始治疗和预测新靶向治疗后的复发或耐药。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Precision Medicine in Lung Cancer: Challenges and Opportunities in Diagnostic and Therapeutic Purposes
Lung cancer is one of the leading causes of cancer death among both men and women, making up almost 25% of all cancer deaths. Precision medicine shows promise for improving many aspects of health and healthcare, including tests, drugs, and other technologies that support innovation, with the possibility of new partnerships with scientists in a wide range of specialties. Non–small-cell lung cancer (NSCLC) has become a prominent example of the success of precision medicine in treating solid tumor malignancies. The first step in this process involves new blood-based diagnostics, which can now noninvasively provide clinically useful information. However, the identification of novel biomarkers that could be used in early diagnosis is urgently needed, especially for guiding initial therapy and predicting relapse or drug resistance following the administration of novel targeted therapies.
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