{"title":"室内氡暴露对居民外周血淋巴细胞DNA损伤的影响","authors":"Cui-lan Zhang","doi":"10.3760/CMA.J.ISSN.0254-5098.2002.05.009","DOIUrl":null,"url":null,"abstract":"Objective\\ To determine the damage of DNA in peripheral blood lymphocytes samples from resident exposure to radon in indoor air. Methods\\ Single cell gel electrophoresis and micronucleus measure methods were used in the present study. Results\\ The results of cell migration frequencies for residents in cave dwellings and normal houses were shown 1\\^68% and 1\\^43%,of calculation by residents were 57 1% and 54 3% respectively.The frequencies of micronucleus results for residents of cave dwellings and normal houses were 1 07‰ and 0\\^78‰ respectively. Conclusion\\ The frequencies of DNA damage and the ratio of micronucleus for residents living in cave dwellings was shown some higher than that of residents living in normal houses, p values close to 0 05.\\;","PeriodicalId":374575,"journal":{"name":"Chinese Journal of Radiation Mediation and Protection","volume":"8 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2002-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"DNA damage in peripheral blood lymphocytes of residents with radon exposure in indoor\",\"authors\":\"Cui-lan Zhang\",\"doi\":\"10.3760/CMA.J.ISSN.0254-5098.2002.05.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective\\\\ To determine the damage of DNA in peripheral blood lymphocytes samples from resident exposure to radon in indoor air. Methods\\\\ Single cell gel electrophoresis and micronucleus measure methods were used in the present study. Results\\\\ The results of cell migration frequencies for residents in cave dwellings and normal houses were shown 1\\\\^68% and 1\\\\^43%,of calculation by residents were 57 1% and 54 3% respectively.The frequencies of micronucleus results for residents of cave dwellings and normal houses were 1 07‰ and 0\\\\^78‰ respectively. Conclusion\\\\ The frequencies of DNA damage and the ratio of micronucleus for residents living in cave dwellings was shown some higher than that of residents living in normal houses, p values close to 0 05.\\\\;\",\"PeriodicalId\":374575,\"journal\":{\"name\":\"Chinese Journal of Radiation Mediation and Protection\",\"volume\":\"8 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2002-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chinese Journal of Radiation Mediation and Protection\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2002.05.009\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Journal of Radiation Mediation and Protection","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2002.05.009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
DNA damage in peripheral blood lymphocytes of residents with radon exposure in indoor
Objective\ To determine the damage of DNA in peripheral blood lymphocytes samples from resident exposure to radon in indoor air. Methods\ Single cell gel electrophoresis and micronucleus measure methods were used in the present study. Results\ The results of cell migration frequencies for residents in cave dwellings and normal houses were shown 1\^68% and 1\^43%,of calculation by residents were 57 1% and 54 3% respectively.The frequencies of micronucleus results for residents of cave dwellings and normal houses were 1 07‰ and 0\^78‰ respectively. Conclusion\ The frequencies of DNA damage and the ratio of micronucleus for residents living in cave dwellings was shown some higher than that of residents living in normal houses, p values close to 0 05.\;