甲状腺手术后低血钙的临床研究及处理

P. Raj, Abhilash, S. Suma, K. Krishnaprasad
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摘要

背景甲状腺切除术后低钙血症是一种严重的并发症。低钙血症可继发于外科创伤、血运断流、意外切除甲状旁腺、再手术。手术被认为是一个危险因素,因为在全甲状腺切除术中,双侧手术操作可能会影响血液供应。本研究旨在前瞻性地研究和分析甲状腺手术后低钙血症的发生率、可能的原因及其处理方法。方法与材料收集2012年11月至2014年10月行甲状腺次全和近全切除术患者的资料,对手术进行细致和有计划的评估和调查。术后第1天、出院时及术后6个月随访术后低钙情况。观察50例患者中有6例(12%)出现术后低钙,无永久性低钙的发生。35例(70%)患者行近全甲状腺切除术,其中1例(2.86%)发生低钙血症,其余5例(35.71%)行全甲状腺切除术。多结节甲状腺低钙率为9%(33例患者中有3例),乳头状癌为20%(5例患者中有1例),滤泡性肿瘤为40%(5例患者中有2例)。结论在甲状腺切除术中保留甲状旁腺及其血液供应,术后低钙血症和永久性甲状旁腺功能减退的发生率是一致的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Clinical Study and Management of Hypocalcemia Following Thyroid Surgery
Background Post-thyroidectomy hypocalcaemia is a serious complication. Hypocalcaemia may occur secondarily to surgical trauma, devascularisation, unintentional removal of parathyroid glands, reoperation. Surgery has been seen as a risk factor, as in total thyroidectomy there is potential blood supply involvement resulting from bilateral surgical manipulation. This study aims to prospectively study and analyse the incidence and possible causes of hypocalcaemia following thyroid surgery, and its management. Method and Mateirals Data was collected from the patients undergoing subtotal and near total thyroidectomies from November 2012 to October 2014 by evaluating and investigating meticulous and planned for surgery. They were follow-up on day one after surgery, at the time of discharge and 6 months after surgery for post-operative hypocalcaemia. Observation 6 out of 50 patients (12%) developed postoperative hypocalcaemia, there was no incidence of permanent hypocalcaemia. Near total thyroidectomy was performed in 35(70%) patients, 1 from them (2.86%) developed hypocalcaemia and the other 5 out of 14 cases (35.71%) underwent total thyroidectomy. The hypocalcaemia was 9% in multinodular goitre (3 out of 33 patients), 20% in papillary carcinoma (1 out of 5 patients) and 40% in follicular neoplasm (2 out of 5 patients). Conclusion When preservation of parathyroid glands and their blood supply is enforced during thyroidectomy, the incidence of postoperative hypocalcaemia and permanent hypoparathyroidism can be consistently deceased.
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