急性上肢动脉栓塞:2年临床经验

M. Atay, M. Gürsoy, V. Bakuy, O. Saydam, A. A. Kavala, Saygin Turkyilmaz, G. Demir, A. Akgül
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引用次数: 0

摘要

目的:肢体血栓栓塞是心血管疾病中发病率和死亡率的重要原因。与下肢动脉相比,上肢急性动脉闭塞较少见,约占所有病例的15-32%。外伤、胶原血管疾病、恶性肿瘤、黏液瘤、锁骨下动脉狭窄、心肌梗死和血栓闭塞性脉管炎常被确定为病因。治疗这些患者的第一选择是手术栓塞切除术。动脉内膜切除术、补片成形术和动脉旁路手术是慢性患者的治疗选择。材料与方法:回顾性分析急诊科收治的58例急性动脉栓塞患者的临床特征及预后,其中女性31例,男性27例。结果:本组患者平均年龄67.05±17.09岁。3例患者发现近端肱动脉血栓形成。其余55例在肱动脉及其远端分支有血栓形成。经急诊室确诊后,应用依诺肝素100单位/kg皮下注射。选择性动脉栓塞切除手术在局部麻醉下进行,所有患者从肘前区进入。2例患者采用隐静脉补片成形术关闭动脉切开术。与术前人口学资料和血栓栓塞病因学比较,21例(36%)患者被诊断为房颤。这些患者未接受房颤随访和治疗。5例(8.6%)患者的病因为恶性肿瘤。4例(6.8%)患者在临床随访期间死亡,其中3例(75%)患者患有房颤。结论:急性外周动脉闭塞是急诊血管手术的重要组成部分。因此,早期诊断和及时手术治疗对治疗效果至关重要。心房颤动(AF)在上肢急性动脉闭塞中占有重要地位,但其他病因如恶性肿瘤也不可忽视。AF合并急性上肢动脉栓塞的患者死亡率较高,必须密切监测这些患者的临床管理和治疗。我们认为,为了找到一种适当的治疗方法,需要发展治疗方式并进行进一步的工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute upper extremity arterial embolism: 2 years of clinical experience -
Objective: Extremity thromboembolism is a serious cause of morbidity and mortality in cardiovascular diseases. Comparing with the lower extremity arteries, upper extremity acute arterial occlusions are rarer and constitute 15-32% of all cases. Trauma, collagen vascular diseases, malignant tumors, myxoma, subclavian artery stenosis, myocardial infarction and thromboangiitis obliterans are often identified as etiologic factors. The first option in the treatment of these patients is surgical embolectomy. Endarterectomy, patchplasty and arterial bypass operations can be counted in treatment options of chronic patients. Material and Methods: In this study, we retrospectively analyzed clinical features and prognosis of 58 patients consisting of 31 women and 27 males who were admitted to our emergency department with acute arterial embolism. Results: Mean age of our group was 67.05±17.09. Proximal brachial artery thrombosis was found in 3 patients. The other 55 patients had thrombosis in the brachial artery and its distal branches. After the diagnosis of patients in the emergency room 100 units/kg of subcutaneous enoxaparine was applied. Selective arterial embolectomy surgery was performed under local anesthesia in all patients with access from the antecubital region. Arteriotomy was closed using saphenous patch plasty technique in two patients. Compared with preoperative demographic data and thromboembolism etiology, 21 (36%) patients were diagnosed as atrial fibrillation. Those patients had not been followed and treated for atrial fibrillation. In 5 (8.6%) patients malignancy was detected as an etiologic factor. Four (6.8%) patients died during their follow-ups in the clinic, 3 (75%) of those patients had an atrial fibrillation. Conclusion: Acute peripheral arterial occlusion constitutes a significant part in emergency vascular surgery. Therefore early diagnosis and prompt surgical treatment are very important for the results. Atrial fibrillation (AF) holds an important place in upper extremity acute arterial occlusion, but other etiological factors such as malignancy is necessary to not forget. AF who has acute upper extremity arterial embolism patients with AF have higher mortality rates and the clinical management and treatment of those patients must be monitored more closely. We believe that the development of treatment modalities and further work needs to be done in order to find an appropriate treatment.
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