马金诺母婴队列社区登革病毒(DENV)中和抗体的胎盘转移和动力学

Anais do IV International Symposium on Immunobiological e VII Seminário Anual Científico e Tecnológico de Bio-Manguinhos Pub Date : 1900-01-01 DOI:10.35259/ISI.SACT.2019_32543

A. Duarte, Stephanie Almeida, K. Paulino, Renata Pedro Saraiva, F. Figueiredo, S. M. Lima, P. Brasil

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引用次数: 0

摘要

答:登革热是一种重要的虫媒病毒，目前在巴西和世界上是一个严重的公共卫生问题。登革热病毒已在该国流行了几十年，自重新引入以来一直是造成流行病的原因。然而，流行病学模式在婴儿的年龄分布和临床症状恶化方面发生了变化，这可能与新生儿中母体抗登革热抗体的存在有关。尽管如此，包括这一人群在内的研究并不常见。在此背景下，在2012年至2014年期间对Manguinhos社区的孕妇和婴儿进行了一项前瞻性研究。

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Placental Transfer and Kinetics of Neutralizing Antibodies for Dengue Virus (DENV) in maternal-infant cohort community of Manguinhos

Introdução: Dengue is an important arbovirus that is currently a serious public health problem in Brazil and in the world. The Dengue virus has been circulating in the country for several decades and it has been responsible for epidemics since its reintroduction. However, the epidemiological pattern has undergone changes in the age distribution and worsening of clinical symptoms in infants, which may be associated with the presence of maternal antiDengue antibodies in neonates. Despite that, the studies including this population group are unfrequently. In this context, a prospective study has been conducted with pregnant and infants from community of Manguinhos between 2012 and 2014.

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Anais do IV International Symposium on Immunobiological e VII Seminário Anual Científico e Tecnológico de Bio-Manguinhos

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