A Randomized Double Blind Placebo Controlled Study Of Prophylactic Gabapentin For Prevention Of Postoperative Pain And Morphine Consumption In Patients Undergoing Mastectomy.

: 50 patients each of ASA I –II were randomly allocated to two study groupsone group received gabapentin (1200mg) and other group received placebo 1 hour prior to surgery. Both groups received morphine (0.1mg/kg) as intraoperative analgesic at induction of anaesthesia. After the completion of mastectomy postoperative analgesia was assessed with visual analogue scale (VAS) method (0cmno pain and 10cmworst possible pain). Rescue analgesic was administered to patients whose VAS was above 3 (morphine 0.1mg/kg).Apart from VAS haemodynamic parameters and oxygen saturation were regularly recorded half hourly for first two hours, then hourly for next 4 hours and then 2 hourly till the patient requested for analgesia postoperatively.