禽畜粪便对土壤水中抗生素残留的生物统计模型

Bin Zhao, Kuiyun Huang, Xia Jiang, Jinming Cao
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Results confirmed that the contamination of vegetables by fecal bacteria is mainly due to the use of poultry manure. INTRODUCTION The large-scale and intensified development of livestock and poultry breeding has resulted in a large number of veterinary antibiotics being used in the aquaculture industry and increasing year by year. Accumulation of antibiotics in the organism. To satisfy the increasing demand for vegetables, despite the poverty of coastal soils and land pressure, farmers tend to intensify production by using mineral and organic fertilizers and pesticides. Today, poultry manure is frequently used as fertilizer in the study area. And poultry manure has been used as effective fertilizers for centuries. It is very low, after the body absorbs a small part, it undergoes metabolic reactions such as hydroxylation, cleavage, and glucuronidation to produce inactive products, and about 60% to 90% pass through feces as it is. Excretion of urine and excrement of livestock and poultry have undoubtedly become one of the main sources of environmental pollution by antibiotics. The drug design of antibiotics is mainly to kill pathogenic pathogens. Once they enter the environment, they will inevitably pose a potential threat to other organisms in the environment. Firstly, the resistant pathogenic bacteria or variant pathogens in livestock and poultry are produced and continuously released into the environment. Secondly, livestock and poultry continue to excrete these antibiotics or their metabolites into the environment, so that drug resistant pathogens and mutant pathogens in the environment are continuously generated. Both of these in turn stimulated the producers to increase the dosage and renew the drug varieties, which resulted in a vicious circle of “drug-contaminated environment → emergence of drug-resistant or mutated pathogens → increased dosages → environmental pollution”. Fertilization by poultry manure has shown an important variance in soil water chemical characteristics. The state for regional soil moisture reserve is the strategic storage of water resources in the district. The distribution of soil moisture directly affects the supply of groundwater resources, determines the amount of water, which is absorbed from the soil and evaporated by the earth’s surface plants, plays a decisive factor for plants’ productivity, and also is regarded as strategic factors influencing the ecological environment security, the economic development and the people’s lives in arid and semi-arid areas ([1]). The intensive use of poultry manure and other animal feces are a significant environmental risk to soil water. Presence of antibiotic and soil water physicochemical properties played key roles in degradation of numerous molecules and other processing. Fertilization is the commonest managing agricultural soils, and for a long time, intensive farming appealed to fertilizer to increase yields. Then livestock and poultry excrement will constitute one of the main reasons for the non-point source pollution of antibiotics Review Article Biostatistical Models of Antibiotic Residues in Soil Water Due to the use of Poultry Manure Bin Zhao1*, Kuiyun Huang1, Xia Jiang2, Jinming Cao3 1College of Science, Hubei University of Technology, Wuhan, Hubei, China 2Hospital, Hubei University of Technology, Wuhan, Hubei, China 3School of Information and Mathematics, Yangtze University, Jingzhou, Hubei, China Central Bringing Excellence in Open Access   Zhao et al. (2018) Email: zhaobin835@nwsuaf.edu.cn 2/6 J Vet Med Res 5(10): 1161 (2018) in China. Therefore, based on the research results in recent years, combining the use of antibiotics in the livestock and poultry industry and the status of residues, this paper analyzes the fate and environmental risks of livestock and poultry excrement in soil, and puts forward the corresponding mathematical model. Darcy law is a fundamental theoretical method to describe the motion law of soil moisture, therefore a variety of Richards equations are deduced. For the nonlinear partial differential equations, the previous research method is to discuss their definite solutions and we commonly can acquire their numerical solution through the numerical method. Whether the analytical solution of Richards equations, which describes the change of soil moisture content with the change of time and space position in Darcy’s law, has been the expectation. If we substitute some empirical representations of hydraulic conductivity and water diffusivity into Richards equations, the exact solution of Richards equation on soil moisture content, soil depth and time is of great significance. Furthermore, the greater parts of antibiotic were found in the soil water by poultry manure. According to the literature, few studies have dealt with the dynamics of antibiotic residues in soil water due to the use of poultry manure. In the past few years, many powerful methods to construct exact solutions of nonlinear evolution equations have been established and developed such as the homogeneous balance method ([2-4]), the (G′/G)-expansion method ([5,6]), the exp-function method ([7,8]) and so on. One of the most effective and direct methods for constructing exact solutions of nonlinear differential equations is the (G′/G)expansion method which is often used in finding exact solutions of nonlinear differential equation. The (G′/G)expansion method, first introduced by Wang et al. ([5]), has been widely used to search for various exact solutions of NLEEs ([9-11]). The (G′/G)expansion method is based on the explicit linearization of nonlinear differential equations for traveling waves with a certain substitution which leads to a second-order differential equation with constant coefficients ([14-16]). Finding an exact solution for Richards equation, by using the (G′/G)expansion method, is the main goal of the present study. BIOSTATISTICAL MODELS AND EXPLANATIONS First of all, we introduce a form of Richards equations as follows: ( ) ( ) ( ) ( ) θ θ θ θ θ θ θ θ ∂   ∂ ∂ ∂ ∂ ∂ ∂ ∂     = + + +       ∂ ∂ ∂ ∂ ∂ ∂ ∂ ∂       K D D D t x x y y z z z , (2.1) Where ( ) θ D denotes water diffusivity; ( ) θ ± K denotes hydraulic conductivity; t denotes time; θ denotes soil moisture content; , , x y z denote coordinate axes. If the soil moisture content is lower than the saturated (unsaturated) moisture content with little change, we take as ( ) θ = D a , where a is a constant. Many researchers have committed themselves to estimating soil hydraulic conductivity, as a result, various empirical representations of hydraulic conductivity are proposed. We assume that ([12,13]) unsaturated hydraulic conductivity is calculated by using the Libardi method, that is ( ) ( ) { } 0 0 exp θ β θ θ = − K K (2.2) Where β is a constant; 0 K and 0 θ are the values of K and θ during steady-state infiltration, respectively. Next, we have intend to simplify equation (2.1), in other words, here we only consider the case that soil moisture flows in the vertical direction, and therefore we have ( ) ( ) θ θ θ θ ∂ ∂ ∂ ∂   = +   ∂ ∂ ∂ ∂   K D t z z z . 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To satisfy the increasing demand for vegetables, despite the poverty of coastal soils and land pressure, farmers tend to intensify production by using mineral and organic fertilizers and pesticides. Today, poultry manure is frequently used as fertilizer in the study area. And poultry manure has been used as effective fertilizers for centuries. It is very low, after the body absorbs a small part, it undergoes metabolic reactions such as hydroxylation, cleavage, and glucuronidation to produce inactive products, and about 60% to 90% pass through feces as it is. Excretion of urine and excrement of livestock and poultry have undoubtedly become one of the main sources of environmental pollution by antibiotics. The drug design of antibiotics is mainly to kill pathogenic pathogens. Once they enter the environment, they will inevitably pose a potential threat to other organisms in the environment. Firstly, the resistant pathogenic bacteria or variant pathogens in livestock and poultry are produced and continuously released into the environment. Secondly, livestock and poultry continue to excrete these antibiotics or their metabolites into the environment, so that drug resistant pathogens and mutant pathogens in the environment are continuously generated. Both of these in turn stimulated the producers to increase the dosage and renew the drug varieties, which resulted in a vicious circle of “drug-contaminated environment → emergence of drug-resistant or mutated pathogens → increased dosages → environmental pollution”. Fertilization by poultry manure has shown an important variance in soil water chemical characteristics. The state for regional soil moisture reserve is the strategic storage of water resources in the district. The distribution of soil moisture directly affects the supply of groundwater resources, determines the amount of water, which is absorbed from the soil and evaporated by the earth’s surface plants, plays a decisive factor for plants’ productivity, and also is regarded as strategic factors influencing the ecological environment security, the economic development and the people’s lives in arid and semi-arid areas ([1]). The intensive use of poultry manure and other animal feces are a significant environmental risk to soil water. Presence of antibiotic and soil water physicochemical properties played key roles in degradation of numerous molecules and other processing. Fertilization is the commonest managing agricultural soils, and for a long time, intensive farming appealed to fertilizer to increase yields. Then livestock and poultry excrement will constitute one of the main reasons for the non-point source pollution of antibiotics Review Article Biostatistical Models of Antibiotic Residues in Soil Water Due to the use of Poultry Manure Bin Zhao1*, Kuiyun Huang1, Xia Jiang2, Jinming Cao3 1College of Science, Hubei University of Technology, Wuhan, Hubei, China 2Hospital, Hubei University of Technology, Wuhan, Hubei, China 3School of Information and Mathematics, Yangtze University, Jingzhou, Hubei, China Central Bringing Excellence in Open Access   Zhao et al. (2018) Email: zhaobin835@nwsuaf.edu.cn 2/6 J Vet Med Res 5(10): 1161 (2018) in China. Therefore, based on the research results in recent years, combining the use of antibiotics in the livestock and poultry industry and the status of residues, this paper analyzes the fate and environmental risks of livestock and poultry excrement in soil, and puts forward the corresponding mathematical model. Darcy law is a fundamental theoretical method to describe the motion law of soil moisture, therefore a variety of Richards equations are deduced. For the nonlinear partial differential equations, the previous research method is to discuss their definite solutions and we commonly can acquire their numerical solution through the numerical method. Whether the analytical solution of Richards equations, which describes the change of soil moisture content with the change of time and space position in Darcy’s law, has been the expectation. If we substitute some empirical representations of hydraulic conductivity and water diffusivity into Richards equations, the exact solution of Richards equation on soil moisture content, soil depth and time is of great significance. Furthermore, the greater parts of antibiotic were found in the soil water by poultry manure. According to the literature, few studies have dealt with the dynamics of antibiotic residues in soil water due to the use of poultry manure. In the past few years, many powerful methods to construct exact solutions of nonlinear evolution equations have been established and developed such as the homogeneous balance method ([2-4]), the (G′/G)-expansion method ([5,6]), the exp-function method ([7,8]) and so on. One of the most effective and direct methods for constructing exact solutions of nonlinear differential equations is the (G′/G)expansion method which is often used in finding exact solutions of nonlinear differential equation. The (G′/G)expansion method, first introduced by Wang et al. ([5]), has been widely used to search for various exact solutions of NLEEs ([9-11]). The (G′/G)expansion method is based on the explicit linearization of nonlinear differential equations for traveling waves with a certain substitution which leads to a second-order differential equation with constant coefficients ([14-16]). Finding an exact solution for Richards equation, by using the (G′/G)expansion method, is the main goal of the present study. BIOSTATISTICAL MODELS AND EXPLANATIONS First of all, we introduce a form of Richards equations as follows: ( ) ( ) ( ) ( ) θ θ θ θ θ θ θ θ ∂   ∂ ∂ ∂ ∂ ∂ ∂ ∂     = + + +       ∂ ∂ ∂ ∂ ∂ ∂ ∂ ∂       K D D D t x x y y z z z , (2.1) Where ( ) θ D denotes water diffusivity; ( ) θ ± K denotes hydraulic conductivity; t denotes time; θ denotes soil moisture content; , , x y z denote coordinate axes. If the soil moisture content is lower than the saturated (unsaturated) moisture content with little change, we take as ( ) θ = D a , where a is a constant. Many researchers have committed themselves to estimating soil hydraulic conductivity, as a result, various empirical representations of hydraulic conductivity are proposed. We assume that ([12,13]) unsaturated hydraulic conductivity is calculated by using the Libardi method, that is ( ) ( ) { } 0 0 exp θ β θ θ = − K K (2.2) Where β is a constant; 0 K and 0 θ are the values of K and θ during steady-state infiltration, respectively. Next, we have intend to simplify equation (2.1), in other words, here we only consider the case that soil moisture flows in the vertical direction, and therefore we have ( ) ( ) θ θ θ θ ∂ ∂ ∂ ∂   = +   ∂ ∂ ∂ ∂   K D t z z z . 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引用次数: 0

摘要

家禽粪便的大量使用是对土壤水的重大环境风险。施用禽粪可影响土壤水分对粪便成分排放的影响。生成了表征土壤水分特征与抗生素关系的载体。土壤湿度生物统计模型采用半经验Richards方程,采用(G′/G)展开法和齐次平衡法得到Richards方程的精确解。然后根据半经验理查兹方程的精确解,建立了包括土壤含水量、土壤深度和时间尺度在内的生物统计模型。在所有土壤、水和家禽粪便样本中至少检出一种抗生素。结果证实,蔬菜受粪便细菌污染的主要原因是使用了禽畜粪便。畜禽养殖业规模化集约化发展,导致养殖业大量使用兽用抗生素,且用量逐年增加。抗生素在生物体中的积累为了满足对蔬菜日益增长的需求,尽管沿海土壤贫瘠,土地压力大,农民倾向于通过使用无机、有机肥料和农药来加强生产。今天,家禽粪便经常被用作研究地区的肥料。几个世纪以来,禽畜粪便一直被用作有效的肥料。其含量极低,人体吸收一小部分后,发生羟基化、裂解、糖醛酸化等代谢反应,生成无活性产物,约60% ~ 90%按其原形排出粪便。畜禽排泄的尿液和粪便无疑已成为抗生素污染环境的主要来源之一。抗生素的药物设计主要是为了杀灭致病性病原体。它们一旦进入环境,必然会对环境中的其他生物构成潜在的威胁。首先,在畜禽体内产生耐药致病菌或变异致病菌,并不断释放到环境中。其次,畜禽不断将这些抗生素或其代谢物排泄到环境中,使环境中的耐药病原体和突变病原体不断产生。这又刺激了生产者增加剂量和更新药物品种,从而形成了“药物污染环境→耐药或突变病原体的出现→剂量增加→环境污染”的恶性循环。禽粪施肥对土壤水分化学特性有重要影响。区域土壤水分储备是区域水资源的战略性储备。土壤水分的分布直接影响地下水资源的供应,决定着地表植物从土壤中吸收和蒸发的水量,对植物的生产力起着决定性的作用,也被视为影响干旱半干旱地区生态环境安全、经济发展和人民生活的战略性因素[1]。家禽粪便和其他动物粪便的大量使用是对土壤水的重大环境风险。抗生素的存在和土壤水的理化性质在许多分子的降解和其他处理中起着关键作用。施肥是最常用的农业土壤管理方法,长期以来,集约化农业依靠施肥来提高产量。畜禽粪便将成为造成抗生素非点源污染的主要原因之一。综述畜禽粪便在土壤水体中抗生素残留的生物统计模型赵斌1*,黄奎云1,江霞2,曹金明3 1湖北工业大学理学院,湖北武汉2湖北工业大学附属医院,湖北武汉3长江大学信息与数学学院,湖北荆州中国中心带来卓越开放获取Zhao等(2018)Email: zhaobin835@nwsuaf.edu.cn 2/6中国兽医医学杂志5(10):1161(2018)。因此,本文基于近年来的研究成果,结合畜禽养殖业抗生素的使用和残留现状,分析畜禽粪便在土壤中的命运和环境风险,并提出相应的数学模型。达西定律是描述土壤水分运动规律的基本理论方法,因此推导出了各种理查兹方程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biostatistical Models of Antibiotic Residues in Soil Water Due to the Use of Poultry Manure
The intensive use of poultry manure is a significant environmental risk to soil water. Manure composition emissions can be effected by soil water with the application of poultry manure. The vectors to represent the relationship between soil water characteristics and antibiotic were generated. A Semi-empirical Richards equation is employed to the biostatistical models of soil moisture while precise solutions of Richards equation obtained by using the (G′/G) expansion method and the homogeneous balance method. Then the biostatistical models which involve several variables including soil moisture content, soil depth and timescales were assumed according to the exact solutions of Semi-empirical Richards equation. At least one antibiotic was detected in all the soil water and poultry manure samples. Results confirmed that the contamination of vegetables by fecal bacteria is mainly due to the use of poultry manure. INTRODUCTION The large-scale and intensified development of livestock and poultry breeding has resulted in a large number of veterinary antibiotics being used in the aquaculture industry and increasing year by year. Accumulation of antibiotics in the organism. To satisfy the increasing demand for vegetables, despite the poverty of coastal soils and land pressure, farmers tend to intensify production by using mineral and organic fertilizers and pesticides. Today, poultry manure is frequently used as fertilizer in the study area. And poultry manure has been used as effective fertilizers for centuries. It is very low, after the body absorbs a small part, it undergoes metabolic reactions such as hydroxylation, cleavage, and glucuronidation to produce inactive products, and about 60% to 90% pass through feces as it is. Excretion of urine and excrement of livestock and poultry have undoubtedly become one of the main sources of environmental pollution by antibiotics. The drug design of antibiotics is mainly to kill pathogenic pathogens. Once they enter the environment, they will inevitably pose a potential threat to other organisms in the environment. Firstly, the resistant pathogenic bacteria or variant pathogens in livestock and poultry are produced and continuously released into the environment. Secondly, livestock and poultry continue to excrete these antibiotics or their metabolites into the environment, so that drug resistant pathogens and mutant pathogens in the environment are continuously generated. Both of these in turn stimulated the producers to increase the dosage and renew the drug varieties, which resulted in a vicious circle of “drug-contaminated environment → emergence of drug-resistant or mutated pathogens → increased dosages → environmental pollution”. Fertilization by poultry manure has shown an important variance in soil water chemical characteristics. The state for regional soil moisture reserve is the strategic storage of water resources in the district. The distribution of soil moisture directly affects the supply of groundwater resources, determines the amount of water, which is absorbed from the soil and evaporated by the earth’s surface plants, plays a decisive factor for plants’ productivity, and also is regarded as strategic factors influencing the ecological environment security, the economic development and the people’s lives in arid and semi-arid areas ([1]). The intensive use of poultry manure and other animal feces are a significant environmental risk to soil water. Presence of antibiotic and soil water physicochemical properties played key roles in degradation of numerous molecules and other processing. Fertilization is the commonest managing agricultural soils, and for a long time, intensive farming appealed to fertilizer to increase yields. Then livestock and poultry excrement will constitute one of the main reasons for the non-point source pollution of antibiotics Review Article Biostatistical Models of Antibiotic Residues in Soil Water Due to the use of Poultry Manure Bin Zhao1*, Kuiyun Huang1, Xia Jiang2, Jinming Cao3 1College of Science, Hubei University of Technology, Wuhan, Hubei, China 2Hospital, Hubei University of Technology, Wuhan, Hubei, China 3School of Information and Mathematics, Yangtze University, Jingzhou, Hubei, China Central Bringing Excellence in Open Access   Zhao et al. (2018) Email: zhaobin835@nwsuaf.edu.cn 2/6 J Vet Med Res 5(10): 1161 (2018) in China. Therefore, based on the research results in recent years, combining the use of antibiotics in the livestock and poultry industry and the status of residues, this paper analyzes the fate and environmental risks of livestock and poultry excrement in soil, and puts forward the corresponding mathematical model. Darcy law is a fundamental theoretical method to describe the motion law of soil moisture, therefore a variety of Richards equations are deduced. For the nonlinear partial differential equations, the previous research method is to discuss their definite solutions and we commonly can acquire their numerical solution through the numerical method. Whether the analytical solution of Richards equations, which describes the change of soil moisture content with the change of time and space position in Darcy’s law, has been the expectation. If we substitute some empirical representations of hydraulic conductivity and water diffusivity into Richards equations, the exact solution of Richards equation on soil moisture content, soil depth and time is of great significance. Furthermore, the greater parts of antibiotic were found in the soil water by poultry manure. According to the literature, few studies have dealt with the dynamics of antibiotic residues in soil water due to the use of poultry manure. In the past few years, many powerful methods to construct exact solutions of nonlinear evolution equations have been established and developed such as the homogeneous balance method ([2-4]), the (G′/G)-expansion method ([5,6]), the exp-function method ([7,8]) and so on. One of the most effective and direct methods for constructing exact solutions of nonlinear differential equations is the (G′/G)expansion method which is often used in finding exact solutions of nonlinear differential equation. The (G′/G)expansion method, first introduced by Wang et al. ([5]), has been widely used to search for various exact solutions of NLEEs ([9-11]). The (G′/G)expansion method is based on the explicit linearization of nonlinear differential equations for traveling waves with a certain substitution which leads to a second-order differential equation with constant coefficients ([14-16]). Finding an exact solution for Richards equation, by using the (G′/G)expansion method, is the main goal of the present study. BIOSTATISTICAL MODELS AND EXPLANATIONS First of all, we introduce a form of Richards equations as follows: ( ) ( ) ( ) ( ) θ θ θ θ θ θ θ θ ∂   ∂ ∂ ∂ ∂ ∂ ∂ ∂     = + + +       ∂ ∂ ∂ ∂ ∂ ∂ ∂ ∂       K D D D t x x y y z z z , (2.1) Where ( ) θ D denotes water diffusivity; ( ) θ ± K denotes hydraulic conductivity; t denotes time; θ denotes soil moisture content; , , x y z denote coordinate axes. If the soil moisture content is lower than the saturated (unsaturated) moisture content with little change, we take as ( ) θ = D a , where a is a constant. Many researchers have committed themselves to estimating soil hydraulic conductivity, as a result, various empirical representations of hydraulic conductivity are proposed. We assume that ([12,13]) unsaturated hydraulic conductivity is calculated by using the Libardi method, that is ( ) ( ) { } 0 0 exp θ β θ θ = − K K (2.2) Where β is a constant; 0 K and 0 θ are the values of K and θ during steady-state infiltration, respectively. Next, we have intend to simplify equation (2.1), in other words, here we only consider the case that soil moisture flows in the vertical direction, and therefore we have ( ) ( ) θ θ θ θ ∂ ∂ ∂ ∂   = +   ∂ ∂ ∂ ∂   K D t z z z . (2.3) By substituting ( ) θ = D a and equation (2.2) into equation (2.3), hence the following semi-empirical Richards equation is obtained:
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