肺炎克雷伯菌肝脓肿合并脓毒性肺栓塞

J. R. Yi, Yeop Yoon, Y. N. Jung, Hee Sook Lee, G. Jo, Ina Jeong
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引用次数: 1

摘要

据报道肺炎克雷伯菌是引起化脓性肝脓肿最常见的病原体。肺炎克雷伯菌肝脓肿常见于糖尿病患者,通常伴有转移性感染,如脑脓肿、眼内炎、肺脓肿、骨髓炎、前列腺炎、坏死性筋膜炎和其他部位感染。尽管脓毒性肺栓塞(SPE)并不常见,但它是肺炎克雷伯菌肝脓肿的严重转移性并发症。胸部计算机断层扫描(CT)在SPE的早期诊断中至关重要;然而,它不能提供明确诊断的基础。一位70岁的男性由于咳嗽和胸片异常被转介到肺科。胸部CT示界限较清,圆形多发结节,周围占优,右肺上叶空腔性肿块,低密度肝囊性肿块。经支气管镜检查及经皮肺穿刺检查均未发现恶性肿瘤。最后,从支气管洗涤标本和血液培养中培养肺炎克雷伯菌。静脉注射碳青霉烯超过3周,随访CT扫描显示肺和肝脏均有改善。我们报告一例肺炎克雷伯菌肝脓肿合并SPE的病例,需要在CT扫描上鉴别诊断血液转移性恶性肿瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Klebsiella pneumoniae Liver Abscess Complicated With Septic Pulmonary Embolism
Klebsiella pneumoniae has been reported to be the most common pathogen causing pyogenic liver abscess. K. pneumoniae liver abscess occurs fairly often in patients with diabetes mellitus, and is commonly associated with metastatic infections such as brain abscess, endophthalmitis, lung abscess, osteomyelitis, prostatitis, necrotizing fasciitis and infection in other sites. Although septic pulmonary embolism (SPE) is uncommon, it is a serious metastatic complication of K. pneumoniae liver abscess. Chest computed tomography (CT) scans are crucial in making the early diagnosis of SPE; however, it does not provide the basis for a definitive diagnosis. A 70-year-old man was referred to the Department of Pulmonology due to cough and an abnormal chest radiography. The chest CT scans revealed relatively well-demarcated, round multiple nodules with peripheral preponderance, cavitary mass in the right upper lobe of the lung and low-density hepatic cystic masses. Bronchoscopic examination and percutaneous needle aspiration of the lung were performed, but there was no evidence of malignancy. Finally, K. pneumoniae was grown from a bronchial washing specimen and blood culture. Intravenous carbapenem was administered over a 3-week period and follow-up CT scans showed improvement in both the lung and the liver. We report a case of K. pneumoniae liver abscess complicated with SPE requiring differential diagnosis of hematogenous metastatic malignancy on CT scans in an elderly patient.
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