现代人与泛穴居人β -珠蛋白基因的尺度图比较

Imen Messaoudi, A. Oueslati, Z. Lachiri
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引用次数: 0

摘要

基因序列使研究人员能够探索相关生物基因组复杂性的问题。ß-珠蛋白基因是一个成功的例子,被广泛应用于比较基因组学和进化分析。在此,我们报告了同源β-珠蛋白基因的DNA序列比较分析结果,在两个分类群:同族(人类)和泛穴居人(黑猩猩)。为此,我们提出了一种基于复Morlet小波变换的DNA序列尺度图表示方法。在将DNA字母转换成信号的编码方法上,我们采用了三核苷酸频率混沌博弈信号(简称FCGS3)。对两幅hbb基因图像的统计分析表明,所提出的方法与DNA比对结果具有良好的相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparing the scalogram images of the Beta-Globin gene in Homosapiens and Pan Troglodytes
Gene sequences have enabled investigators to explore questions of genomes complexity in related organisms. The ß-globin gene is a successful example which is widely used in comparative genomics and evolutionary analyses. Herein, we report the results of a comparative DNA sequence analysis of the homologous β-globin genes in two taxa: Homosapies (human) and Pan Troglodytes (Chimpanzee). To this end, we propose a new method to represent the DNA sequences into scalogram images based on the complex Morlet wavelet transform. As for the coding method which transforms the DNA letters into a signal, we use the Frequency Chaos Game Signal of trinucleotides (coined FCGS3). The statistical analysis of the two HBB-gene images shows good correlation between the proposed method and the DNA alignment result.
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