一项初步研究表明,使用棕榈仁油可以降低低收入国家烧伤伤口护理的成本

M. H. Ibrahim, H. Aminu, M. Yakubu, A. Muhammad, Rilwan O Maleeq
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引用次数: 1

摘要

简介:棕榈仁油,乳木果油和蜂蜜传统上用于治疗西非的各种疾病,但没有关于乳木果油和棕榈仁油烧伤伤口愈合活性的科学报道,尽管蜂蜜已被用于治疗烧伤伤口。本研究旨在比较这些有机化合物(棕榈仁油、乳木果油和蜂蜜)与常规磺胺嘧啶银和聚维酮碘乳膏治疗实验室白化病大鼠真皮深层或全层烧伤创面的愈合效果。材料与方法:体重250 ~ 300 g的大鼠25只,随机分为5组。在大鼠背部形成约225 mm2深皮烧伤创面或全厚烧伤创面。烧伤创面每隔一天包扎一次,第1组用蜂蜜处理;(2)乳木果油;组(3)棕榈仁油;(4) 1%磺胺嘧啶银组和(5)5%聚维酮碘乳膏组。在敷料时观察上皮化并测量收缩。结果:棕榈仁和聚维酮碘乳膏治疗组创面在第6天迅速缩小(P≤0.05),第8天创面完全闭合,乳木果油治疗组创面在第10天明显收缩,仅在第14天创面闭合。结论:棕榈仁油是一种价格合理且易于获得的外用剂,具有快速烧伤创面愈合的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The cost of burn wound care in low-income nations could be reduced with the use of palm kernel oil: A preliminary study
INTRODUCTION: Palm kernel oil, Shea butter and honey are used traditionally for the treatment of variety of ailments in West Africa, but there are no scientific report on burn wound healing activity of Shea butter and palm kernel oil, although honey has been in use for the treatment of burn wound. This study aim to compare the wound healing effect of these organic compounds (palm kernel oil, Shea butter and honey) in the treatment of deep dermal or full thickness burn wound to the conventional Silver sulfadiazine and povidone iodine creams in laboratory albino rats. MATERIALS AND METHODS: 25 rats weighing from 250–300 grams were randomly divided into five groups. About 225 mm2 deep dermal burn/or full thickness burn wound was created on the dorsum of the rats. The burn wound were dressed every alternate day with group (1) treated with honey; group (2) Shea butter; group (3) palm kernel oil; group (4) 1% silver sulfadiazine and group (5) 5% povidone iodine cream. Epithelialization observed and contraction was measured at the time of the dressing. FINDINGS: There was rapid reduction in the wound size by day 6 (P≤0.05) in the palm kernel and povidone iodine cream treated group and by day 8 the wound in both group were completely closed, the Shea butter treated group wound shows significant contraction by day 10 and the wound were closed only from day 14 on ward. CONCLUSION: Palm kernel oil is an affordable and readily available topical agent that holds potential for rapid burn wound healing.
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