功能化氮化硼在生物技术中的应用

Hélio Ribeiro, Paula von Cardoso Randow, Diego N. Vilela, Milene Adriane Luciano, Lidia Maria de Andrade
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引用次数: 9

摘要

氮化硼以其独特的化学、物理和生物特性,受到了科技界的广泛关注。然而,就其潜在应用而言,其结构质量和在不同宿主系统中的兼容性有很强的依赖性。由于这些不同的纳米结构在水和有机溶剂中的分散性较低,因此使用它们面临一些挑战;因此,它的化学修饰是赋予它们特异性的重要步骤。因此,控制其表面(物理或化学)的能力对于探索和构建超分子结构的纳米工程至关重要。在本章中,我们报道了不同的氮化硼功能化过程,以及它们在疫苗、近距离治疗或药物递送中作为佐剂的重要用途。此外,还报道了一些重要的理论研究,证明了纳米医学中使用的不同功能化可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Functionalized Boron Nitride Applications in Biotechnology
Due to its interesting chemical, physical, and biological properties, boron nitride has received considerable attention by the scientific and technological communities. However, there is a strong dependency of its structural quality and compatibility in different host systems, regarding its potential applications. The use of these different nanostructures involves several challenges due to their low dispersibility in water and organic solvents; thus, its chemical modification is an important step that gives them specificity. Therefore, the ability to control their surface (physically or chemically) is essential for exploring and building blocks in the nanoengineering of supramolecular structures. In this chapter, we report different boron nitride functionalization processes, as well as their important uses as adjuvants in vaccines, brachytherapy, or drug delivery. Besides some important theoretical studies that have demonstrated the different functionalization possibilities for use in nanomedicine, are also reported.
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