一个间期收缩环使原始生殖细胞重塑，从而使大量细胞质重塑

The Journal of Cell Biology Pub Date : 2019-12-05 DOI:10.1083/jcb.201906185

Chelsea Maniscalco, Allison E. Hall, J. Nance

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引用次数: 9

摘要

Maniscalco等人表明，原始生殖细胞通过组装一个非有丝分裂的收缩环来重塑。环的形成需要RhoGEF ECT-2和它的激活剂NOP-1，但不需要中央纺锤子，它激活ECT-2在有丝分裂期间定位细胞动力学收缩环。

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An interphase contractile ring reshapes primordial germ cells to allow bulk cytoplasmic remodeling

Maniscalco et al. show that primordial germ cells remodel by assembling a nonmitotic contractile ring. Ring formation requires the RhoGEF ECT-2 and its activator NOP-1 but not centralspindlin, which activates ECT-2 to position the cytokinetic contractile ring during mitosis.

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来源期刊

The Journal of Cell Biology

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