孕妇青光眼:治疗特点

T. Y. Matnenko, A. V. Yurlagina, O. I. Lebedev
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摘要

本文就孕妇青光眼的特点、发病率、发病机制、保守治疗、激光治疗和手术治疗的可能性进行综述。本文献综述的目的是研究妊娠期青光眼患者的治疗特点。青光眼是一大类眼病,其特征是视力损害的逐渐发展和视神经的萎缩。该病在40岁以上人群中最为常见,但由于生殖技术的进步,诊断方法的可用性以及临床意识的提高,眼科医生治疗孕妇青光眼的频率增加。孕妇眼压升高正变得越来越普遍,因此是一个紧迫的问题。第一次眼压升高的孕妇人数有增加的趋势。以前发现的病理儿童或继发性青光眼由于以前的眼部疾病或严重的躯体病理是一个特殊的类别的患者。此类患者经常遇到,需要眼科医生和妇科医生的密切监督。抗青光眼药物的证据基础很小;有在动物身上进行的临床实验,其结果并不总是适用于人类,还有回顾性研究。医生的武器库目前包括一些可能对胎儿有副作用的药物,以及激光和手术治疗。没有标准的治疗方法,因此每个病例都应该单独考虑,并了解药物的生理、作用机制及其可能的影响。因此,妊娠期和哺乳期青光眼是一个严重的医学问题,其解决需要跨学科的医学方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Glaucoma in pregnant women: features of treatment
This review provides information on the features, incidence, pathogenetic mechanism, possibilities of conservative, laser and surgical treatment of glaucoma in pregnant women. The purpose of this literature review is to study the features of managing patients with glaucoma during pregnancy. Glaucoma is a large group of eye diseases characterized by a gradual development of visual impairments and atrophy of the optic nerve. The pathology is most common among the population over 40 years old, but due to the advancement of reproductive technologies, the availability of diagnostic methods, as well as high clinical awareness, the frequency of ophthalmologists managing glaucoma in pregnant women increases. Elevated intraocular pressure in pregnant women is becoming more common and, therefore, is an urgent problem. There is a trend towards an increase in the number of pregnant women who experienced elevated intraocular pressure for the first time. Previously identified pathology in childhood or secondary glaucoma due to previous ophthalmic diseases or severe somatic pathology is a special category of patients. Such patients are encountered regularly and require close supervision by both an ophthalmologist and a gynecologist. The evidence base for antiglaucoma drugs is small; there are clinical experiments on animals, which results do not always carry over to humans, and retrospective studies. The doctor's arsenal presently includes a number of drugs that have possible side effects for the fetus, as well as laser and surgical treatment. There is no standard treatment, so each case should be considered individually with an understanding of the physiology, mechanism of action of the drugs and their possible effects. Therefore, glaucoma during pregnancy and lactation is a serious medical problem, and its solution depends on interdisciplinary medical approach.
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