接受他莫昔芬化疗或激素治疗的妇女牙周全口消毒后的骨影像学评价

Rahyza I. F. Assis, Manoelito F S Junior, Marciel Silva dos Santos, T. Pereira, A. Feitosa, Sérgio Lins de Azevedo-Vaz
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引用次数: 1

摘要

目的:观察三苯氧胺(Tamoxifen, TAM)化疗和激素治疗期间女性患者牙周全口消毒(FMD)后牙槽骨水平的变化。材料和方法:这是一项不受控制的临床试验,使用了抗肿瘤治疗(CHE和TAM)和非手术牙周口蹄疫治疗的方便样本。x线检查包括4张咬翼x线片和6张尖周x线片,分别于牙周治疗前(T0)、3 (T3)和6 (T6)个月按平行标准技术拍摄。每颗牙近端间区牙槽嵴水平由两个校准的观测者用放大镜和数字卡尺测量。采用Friedman检验对各实验组的三次评分进行统计学分析(p < 0.05)。结论:接受他莫昔芬化疗和激素治疗的患者在牙周FMD治疗6个月后,牙槽骨水平有所改善。目前的抗肿瘤治疗不影响牙周治疗的结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Radiographic Bone Evaluation after Periodontal Full Mouth Disinfection Treatment in Women Undergoing Chemotherapy or Hormone Therapy with Tamoxifen
Objective: To radiographically evaluate the alveolar bone level after periodontal full mouth disinfection (FMD) treatment in women during chemotherapy (CHE) and hormone therapy with Tamoxifen (TAM). Material and Methods: This is an uncontrolled clinical trial with a convenience sample of women in antineoplastic treatment (CHE and TAM) and non-surgical periodontal FMD treatment. The Radiographic examination consisted of four bitewing radiographs and six periapical radiographs of the upper and lower anterior teeth, acquired according to the parallelling standard technique at three times: before (T0), 3 (T3) and 6 (T6) months after periodontal treatment. The alveolar crest level in the interproximal area of each tooth was measured by two calibrated observer using magnifying glass and digital caliper. Statistical analysis was performed for evaluation of the three times in each experimental group using the Friedman test (p 0.05). Conclusion: Patients undergoing chemotherapy and hormone therapy with Tamoxifen showed better alveolar bone levels after six months of periodontal FMD treatment. The current antineoplasic therapy did not influence the results obtained with periodontal treatment.
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