头颈部肉瘤-我们在摩洛哥拉巴特三级护理中心的经验

Rajae Borki, S. Nitassi, A. Ayoubi, R. Bencheikh, A. Oujilal, A. Benbouzid, L. Essakalli
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引用次数: 1

摘要

头颈部肉瘤是一种罕见的恶性肿瘤。处理这些肉瘤的困难需要多学科团队的干预来改善预后。我们研究的目的是报告我们的系列(流行病学、组织学和进展特征)并评估我们的治疗结果。患者和方法:本研究对Rabat大学医院耳鼻喉科和颌面外科5年(2010-2015)42例头颈部肉瘤进行回顾性研究。所有肉瘤均经免疫组化组织学检查证实。结果:男性29例,女性13例。患者的平均年龄为35.5岁(年龄极值:13岁和70岁)。21例患者均行CT扫描和MRI扫描。远程扩展评估显示8例肺转移。最常见的组织学类型是滑膜肉瘤,13例(30.9%),其次是骨肉瘤(21.2%)。在手术加放疗的基础上,19例骨肉瘤治愈。12例患者出现完全缓解。结论:头颈部肉瘤是一种罕见的恶性肿瘤,预后较差。治疗方法结合了手术和放化疗。然而,在缺乏足够和有效的治疗方案的情况下,有必要及时确定手术指征,以确保尽可能完整的切除。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Head and Neck Sarcomas - Our Experience at a Tertiary Care Center in Rabat, Morocco
Introduction : Head and neck sarcomas are rare, malignant and very heterogeneous tumors. The difficulty to manage these sarcomas requires the intervention of a multidisciplinary team to improve the prognosis. The aim of our study is to report our series (epidemiological, histological and progressive characteristics) and evaluate our treatment results. Patients and methods : This is a retrospective study on 42 cases of head and neck sarcomas, assembled at ENT and Maxillofacial Surgery department in the University Hospital of Rabat, for a period of 5 years (2010-2015). All sarcomas were confirmed by histological examination with immunohistochemical study. Results : There were 29 men and 13 women. The average age of our patients was 35.5 years (extremes of age: 13 and 70 years). All patients received a CT scan with MRI scan in 21 cases. A remote extension assessment showed lung metastases in 8 cases. The most frequently found histological type was synovial sarcoma, which was noted in 13 patients (30.9%) followed by osteosarcoma (21.2%). The osteosarcoma treatment was curative in 19 cases, based on surgery with radiotherapy. Total remission was noted in twelve patients. Conclusion : Head and neck sarcomas are rare and very aggressive cancers with poor prognosis. The treatment approach combines surgery and chemoradiation. However, in the absence of adequate and effective treatment protocols, it is necessary to establish a surgical indication in time to ensure excision as complete as possible.
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