Service-oriented, holonic environment control of radiopharmaceutical production facilities

The paper describes a new holonic solution for the design of generic Facility Environment Conditioning and Control Systems (HFES) based on modelling processes as environment services (EServices) and implementation in multi-agent framework. This approach allows for the customization of: data acquisition, correlation between cleanroom parameters, HVAC channel control and influencing the radiopharmaceuticals production, depending on: (1) facility layout, 2) cleanroom models, 3) relative constraints between parameters of adjacent workspaces, 4) heat and ventilation HVAC channel process models, 5) desired performance indicators of the facility's global control system: basic (stability, precision); for safety and agility (robustness, sensitivity, nervousness, high availability), and 6) control strategies and laws of compensators. The control solution and implementing framework use distributed intelligence delegated to the decentralized control layer of service-oriented agents acting as informational instances of holons, apply web service principles for the cooperation between holons, with the scope of total integration of facility environment processes.