EBOCA:生物医学概念关联本体证据

Andrea 'Alvarez P'erez, Ana Iglesias-Molina, L. Santamar'ia, Mar'ia Poveda-Villal'on, Carlos Badenes-Olmedo, Alejandro Rodr'iguez-Gonz'alez
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引用次数: 3

摘要

。现在有大量的在线文档数据源可用。缺乏结构化和格式之间的差异是自动提取信息的主要困难,这也对其使用和重用产生了负面影响。在生物医学领域,DISNET平台的出现为研究人员提供了一种资源,可以通过大规模异构资源获取人类疾病网络范围内的信息。特别是在这个领域,不仅要提供从不同来源提取的信息,而且要提供支持它的证据,这一点至关重要。本文提出了EBOCA,一个描述(i)生物医学领域概念和它们之间关联的本体,以及(ii)支持这些关联的证据;目的是提供一种模式,以改善该领域证据和生物医学关联的出版和描述。已经成功地评估了本体,以确保没有错误和建模缺陷,并且满足先前定义的功能需求。根据提出的本体对来自DISNET子集的测试数据和文本的自动关联提取进行转换,以创建可用于实际场景的知识图,该知识图也用于评估所提出的本体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
EBOCA: Evidences for BiOmedical Concepts Association Ontology
. There is a large number of online documents data sources available nowadays. The lack of structure and the differences between formats are the main difficulties to automatically extract information from them, which also has a negative impact on its use and reuse. In the biomedical domain, the DISNET platform emerged to provide re-searchers with a resource to obtain information in the scope of human disease networks by means of large-scale heterogeneous sources. Specif-ically in this domain, it is critical to offer not only the information extracted from different sources, but also the evidence that supports it. This paper proposes EBOCA, an ontology that describes (i) biomedical domain concepts and associations between them, and (ii) evidences supporting these associations; with the objective of providing an schema to improve the publication and description of evidences and biomedical associations in this domain. The ontology has been successfully evaluated to ensure there are no errors, modelling pitfalls and that it meets the previously defined functional requirements. Test data coming from a subset of DISNET and automatic association extractions from texts has been transformed according to the proposed ontology to create a Knowledge Graph that can be used in real scenarios, and which has also been used for the evaluation of the presented ontology.
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