女性

A. Motz
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引用次数: 0

摘要

艾滋病毒阳性的南非妇女在常规产前护理中实现了病毒抑制,但后来经历了病毒血症发作(病毒载量为1000拷贝/mL),检查了抗逆转录病毒药物的存在,并将其归类为“非粘附者”或“次优粘附者”。在几个时间点对妇女进行耐药突变(DRM)检测,并在产后36-60个月进行病毒载量检测。次优依从者更有可能在病毒血症发作时检测到DRM (p=0.03),以及随后的病毒血症时间点(p=0.05)。检测到DRM的女性与未检测到DRM的女性在36-60个月后的病毒抑制水平没有差异(p=0.5)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Women
HIV+ South African women who achieved viral suppression during routine antenatal care, but later experienced a viremic episode (viral load>1000 copies/mL), were examined for presence of ARVs and classified as ‘non-adherers’ or ‘suboptimal adherers’. Women were tested for drug-resistance mutations (DRM) at several time points, and underwent viral load testing 36-60 months postpartum. Suboptimal adherers were more likely to have DRM detected at their viremic episode (p=0.03), and a subsequent viremic time point (p=0.05). There was no difference in levels of viral suppression 36-60 months later in women with DRM detected versus women who had no evidence of DRM (p=0.5).
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