{"title":"模拟生物化学相互作用在微流体辅助多孔硅微阵列光学传感","authors":"E. Orabona, I. Rea, I. Rendina, L. de Stefano","doi":"10.1109/IWBP.2011.5954860","DOIUrl":null,"url":null,"abstract":"In this paper we present a numerical model for the design of microfluidic assisted porous silicon microarray for the optical monitoring of biomolecular interactions. The kinetic binding is studied as a function of several physical, chemical and geometrical parameters. Optimization conditions in order to maximize the sensor response and increase the accuracy are given.","PeriodicalId":142421,"journal":{"name":"2011 International Workshop on Biophotonics","volume":"31 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2011-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Modelling biochemical interactions in a microfluidic assisted porous silicon microarray for optical sensing\",\"authors\":\"E. Orabona, I. Rea, I. Rendina, L. de Stefano\",\"doi\":\"10.1109/IWBP.2011.5954860\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this paper we present a numerical model for the design of microfluidic assisted porous silicon microarray for the optical monitoring of biomolecular interactions. The kinetic binding is studied as a function of several physical, chemical and geometrical parameters. Optimization conditions in order to maximize the sensor response and increase the accuracy are given.\",\"PeriodicalId\":142421,\"journal\":{\"name\":\"2011 International Workshop on Biophotonics\",\"volume\":\"31 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2011-06-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2011 International Workshop on Biophotonics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/IWBP.2011.5954860\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2011 International Workshop on Biophotonics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IWBP.2011.5954860","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Modelling biochemical interactions in a microfluidic assisted porous silicon microarray for optical sensing
In this paper we present a numerical model for the design of microfluidic assisted porous silicon microarray for the optical monitoring of biomolecular interactions. The kinetic binding is studied as a function of several physical, chemical and geometrical parameters. Optimization conditions in order to maximize the sensor response and increase the accuracy are given.