Gadjah Mada医院用于COVID-19患者行走抽样的GAMA拭子取样室的开发

H. Nirwati, D. Nugrahaningsih, S. Siswanto, M. Bawono, Titien Budhiaty, S. Wibowo, R. Sumiharto
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引用次数: 0

摘要

从COVID-19患者的鼻咽和口咽收集拭子样本对于检测SARS-CoV-2至关重要。这个过程可能产生足够的液滴。由于SARS-CoV-2通过飞沫传播,因此必须仔细进行拭子取样,以防止传播给医护人员或交叉污染环境的风险。GAMA棉签取样室(GSSC)是一个正压室,设计用于收集棉签样本,包括位于室内的医护人员,而患者在室外。该室的设计是为了尽量减少由于泄漏或打开或关闭门时气溶胶暴露给医护人员的风险。因此,卫生保健工作者不需要使用完整的个人防护装备(PPE),因为他们在没有隔离室的情况下收集拭子样本。经过几次检查安全性和枪膛功能的测试后,GSSC在Gadjah Mada医院使用。该实验室对51名无症状患者、72名疑似患者和284名志愿者进行了为期10周的拭子取样。所有无症状患者标本逆转录聚合酶链反应(RT-PCR)检测结果均为阴性,而72例疑似患者中2例(2.8%)和284例志愿者中4例(1.4%)的RT-PCR检测结果为阳性。使用GSSC可以简化拭子取样,还可以减少对个人防护装备和负压隔离室的需求,这在当前大流行情况下是有限的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The development of GAMA Swab sampling chamber for walk-through sampling in patients with COVID-19 at Gadjah Mada Hospital
Collecting swab samples from the nasopharynx and oropharynx of patients with COVID-19 is essential in detecting SARS-CoV-2. This procedure potentially produces sufficient droplets. Since SARS-CoV-2 is transmitted through droplets, swab sampling has to be done carefully to prevent the risk of transmission to healthcare workers or the cross-contamination to the environment. The GAMA Swab Sampling Chamber (GSSC) is a positive-pressure chamber designed for collecting swab samples involving the healthcare worker positioned inside, while the patient is outside the chamber. The chamber is designed to minimize the risk of aerosol exposure to the healthcare worker due to leakage or when opening or closing the door. Accordingly, the healthcare worker does not need to use complete personal protective equipment (PPE) as they do when collecting swab samples without the chamber. After several tests to check the safety and the chamber’s function, the GSSC was used at Gadjah Mada Hospital. This chamber had been used to swab 51 asymptomatic patients, 72 suspected patients, and 284 voluntary persons for ten weeks. The results of reverse transcription-polymerase chain reaction (RT-PCR) examination of all samples from asymptomatic patients were negative, while 2 of 72 suspected patients (2.8%) and 4 of 284 voluntary persons (1.4%) had positive RT-PCR results. The use of GSSC can simplify the swab sampling, also reduces the need for PPE usage and a negative pressure isolation room which are limited in the current pandemic situation.
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