新生儿破伤风:来自埃塞俄比亚迪拉大学转诊医院的病例系列

Shimelis Bonsa, Robel Hussen Kabythmer, Afomia Tadesse Tefera
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引用次数: 0

摘要

背景:新生儿破伤风是一种致命的感染,导致发展中国家新生儿死亡率的7-8%。世卫组织将新生儿破伤风定义为一种疾病,发生在出生头2天具有正常吸吮能力,在出生后第3至28天出现吸吮失败,并出现僵硬和痉挛。尽管埃塞俄比亚在2017年宣布消除孕产妇和新生儿破伤风,但在新生儿重症监护室仍有大量新生儿出现这一问题。方法:本综述对2018年9月11日至2020年9月11日在迪拉大学医院新生儿重症监护室收治的7例新生儿破伤风病例的临床资料、人口统计学和结局进行了分析。结果:所有产妇均在非熟练接生员的陪同下在家分娩,使用当地刀片或小刀剪断脐带。母亲的中位年龄为26岁,七人中有两人接受了产前护理(ANC)随访,并接种了两剂破伤风类毒素(TT)疫苗。发热、不能吸吮、痉挛、抽搐是常见的临床表现。总死亡率为70%。结论:应继续重视产前破伤风免疫接种和安全分娩做法。照顾新生儿的临床医生应了解新生儿破伤风的表现,以便及早诊断这些患者并采取适当的救生管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neonatal Tetanus: case series from Dilla univeristy referal hospital, Ethiopia
Background: Neonatal tetanus is a deadly infection leading to 7-8% of neonatal mortality in de-veloping countries. WHO defines Neonatal tetanus as an illness in a child who has the normal ability to suck in the first 2 days of life, presented with failure to suck between 3rd and 28th days of life and has rigidity and spasms? Though Ethiopia declared maternal and neonatal tetanus elimination in 2017, there has been significant number of neonates presenting with this problem in Neonatal ICU’sMethods: This review characterized clinical profile, demography and outcome of seven neona-tal tetanus cases admitted at Dilla University hospital, neonatal ICU from September 11, 2018 to September11, 2020.Results: All mothers gave birth at home with unskilled birth attendant, local blade or knife was used to cut the cord. Median age for mothers was 26 years and two out of seven had antenatal care (ANC) follow up and took Two doses of tetanus toxoid (TT) vaccine. Fever, failure to suck, spasm and convulsions were the common presenting symptoms. The overall mortality was 70%.Conclusion: Continuous emphasis on antenatal tetanus immunization and safe delivery practic-es should be maintained. Clinicians caring for neonates should be aware of the presentations of neonatal tetanus to allow them to diagnose these patients early and initiate appropriate lifesaving management.
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