蓝光照射对人工胆红素溶液的影响

S. Herwiningsih, D. Anggraeni, Mustika Dewi
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引用次数: 0

摘要

高胆红素血症是新生儿皮肤和粘膜中未结合胆红素的积累。光疗常用于利用可见光治疗高胆红素血症。本研究旨在探讨蓝光照射对人工胆红素溶液的影响。以甲基红粉和乙酸为原料制备人工胆红素溶液。测量飞利浦52型荧光灯管发出的蓝光的光谱和强度,分别照射浓度为5、10、15、20和30 mg/dl的人工胆红素溶液。用分光光度计测定辐照前后溶液的透射强度。结果表明,荧光灯管发出的蓝光光谱符合作为光疗光源的标准。最小所需强度在距离灯35 - 40厘米处获得。蓝光照射对人工胆红素溶液的影响在溶液浓度较低时较为明显,照射前后溶液透射强度差异较大。为了使光疗有效,需要更长的照射时间或更高的照射强度以达到更高的浓度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE EFFECT OF BLUE LIGHT IRRADIATION ON ARTIFICIAL BILIRUBIN SOLUTION
Hyperbilirubinemia is an accumulation of unconjugated bilirubin in the skins and mucous membrane of newborns. Phototherapy is often used to treat hyperbilirubinemia by using visible light. The aim of this study was to investigate the effect of blue light irradiation on artificial bilirubin solution. The artificial bilirubin solution was prepared using methyl red powder and acetic acid. The blue light emitted from fluorescent light tube model 52 (Philips) were measured its spectrum and intensity, and then used to irradiate the artificial bilirubin solution with concentration of 5, 10, 15,20 and 30 mg/dl. The transmitted intensity of the solution before and after irradiation was measured using spectrophotometer. The result shows that the spectrum of the blue light emitted from the fluorescent tube light met the criteria to be used as phototherapy light source. The minimum required intensity is obtained at distance of 35 – 40 cm from the lamp. The effect of blue light irradiation on artificial bilirubin solution is obviously observed in a low solution concentration, indicated by a higher difference of the transmitted intensity of the solution before and after irradiation. A longer irradiation or a higher intensity is required for a higher concentration in order the phototherapy to be effective.
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