4. 建立正常乳腺组织活检标本收集的实践和伦理问题——nowac后基因组队列的一部分

Sanda Krum-Hansen, K. Olsen
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引用次数: 1

摘要

对于以组织为基础的乳腺癌研究来说,获得真正正常的、有良好注释的组织可能是一个挑战。为了满足这一需求,我们从健康的绝经后妇女中收集了368例乳腺组织活检和缓冲血液样本。志愿者是挪威妇女和癌症(NOWAC)后基因组队列的一部分,通过国家乳房x光检查项目招募。用于基因表达分析的NOWAC正常乳腺组织生物库将为病例对照研究的比较提供正确的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
4. Practical and Ethical Issues in Establishinga Collection of Normal Breast Tissue Biopsies—Part of the NOWACPost-Genome Cohort
For tissue-based studies of breast cancer, getting access to truly normal, well-annotated tissue can be a challenge. To address that need, we collected 368 breast tissue biopsies and buffered blood samples from healthy postmenopausal women. Volunteers were part of the Norwegian Women and Cancer (NOWAC) Postgenome cohort, recruited through the national mammography screening program. The NOWAC normal breast tissue biobank for gene expression analysis will provide a correct basis for comparison in case-control studies.
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