{"title":"一种基于微流控芯片和GMR传感器的高灵敏度心脏多生物标志物检测系统","authors":"W. Huo, Y. Gao, L. Zhang, S. Shi","doi":"10.1109/INTMAG.2015.7156941","DOIUrl":null,"url":null,"abstract":"Giant magnetoresistance (GMR) is a quantum mechanical magnetoresistance effect observed in thin-film structures composed of alternating ferromagnetic and non-magnetic conductive layers. Today GMR has been used in various fields including detecting DNA hybridization and pathogenic microorganism[1], screening diagnostic biomarkers[2], detecting HBV genotypes[3], and so on. NT-proBNP is an established risk factor in patients with heart failure or coronary disease. cTnI is considered the standard biomarker for acute myocardial infarction(AMI). The combined detection of NT-proBNP and cTnI could improve the sensitivity and specificity in clinical diagnosis of myocardial injury.","PeriodicalId":381832,"journal":{"name":"2015 IEEE Magnetics Conference (INTERMAG)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2015-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"A novel high-sensitivity cardiac multi-biomarkers detecting system based on microfluidic chip and GMR sensor\",\"authors\":\"W. Huo, Y. Gao, L. Zhang, S. Shi\",\"doi\":\"10.1109/INTMAG.2015.7156941\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Giant magnetoresistance (GMR) is a quantum mechanical magnetoresistance effect observed in thin-film structures composed of alternating ferromagnetic and non-magnetic conductive layers. Today GMR has been used in various fields including detecting DNA hybridization and pathogenic microorganism[1], screening diagnostic biomarkers[2], detecting HBV genotypes[3], and so on. NT-proBNP is an established risk factor in patients with heart failure or coronary disease. cTnI is considered the standard biomarker for acute myocardial infarction(AMI). The combined detection of NT-proBNP and cTnI could improve the sensitivity and specificity in clinical diagnosis of myocardial injury.\",\"PeriodicalId\":381832,\"journal\":{\"name\":\"2015 IEEE Magnetics Conference (INTERMAG)\",\"volume\":\"17 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-07-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2015 IEEE Magnetics Conference (INTERMAG)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/INTMAG.2015.7156941\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2015 IEEE Magnetics Conference (INTERMAG)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/INTMAG.2015.7156941","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A novel high-sensitivity cardiac multi-biomarkers detecting system based on microfluidic chip and GMR sensor
Giant magnetoresistance (GMR) is a quantum mechanical magnetoresistance effect observed in thin-film structures composed of alternating ferromagnetic and non-magnetic conductive layers. Today GMR has been used in various fields including detecting DNA hybridization and pathogenic microorganism[1], screening diagnostic biomarkers[2], detecting HBV genotypes[3], and so on. NT-proBNP is an established risk factor in patients with heart failure or coronary disease. cTnI is considered the standard biomarker for acute myocardial infarction(AMI). The combined detection of NT-proBNP and cTnI could improve the sensitivity and specificity in clinical diagnosis of myocardial injury.
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