COVID-19的发病率及其与空气污染暴露的关系:来自荷兰的证据

B. Andrée
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引用次数: 89

摘要

严重急性呼吸综合征冠状病毒2的快速传播导致世界各地出现了几个热点。其中一些位于空气污染严重的地区。本研究调查了荷兰355个城市的颗粒物暴露与COVID-19发病率之间的关系。结果表明,直径小于2.5的大气颗粒物是新冠肺炎确诊病例数和相关住院人数的高度显著预测因子。估计表明,当污染浓度增加20%时,预计的COVID-19病例将增加近100%。在存在与健康相关的先决条件、症状严重程度的替代指标和人口控制变量的数据时,空气污染与病例发病率之间的关联是强有力的。这些结果是通过对大气颗粒物的地面测量和卫星测量以及来自替代日期的COVID-19数据获得的。研究结果要求进一步调查空气污染与SARS-CoV-2感染风险之间的关系。如果颗粒物在COVID-19发病率中发挥重要作用,那么它将对防止传播所需的缓解战略产生重大影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence of COVID-19 and Connections with Air Pollution Exposure: Evidence from the Netherlands
The fast spread of severe acute respiratory syndrome coronavirus 2 has resulted in the emergence of several hot-spots around the world. Several of these are located in areas associated with high levels of air pollution. This study investigates the relationship between exposure to particulate matter and COVID-19 incidence in 355 municipalities in the Netherlands. The results show that atmospheric particulate matter with diameter less than 2.5 is a highly significant predictor of the number of confirmed COVID-19 cases and related hospital admissions. The estimates suggest that expected COVID-19 cases increase by nearly 100 percent when pollution concentrations increase by 20 percent. The association between air pollution and case incidence is robust in the presence of data on health-related preconditions, proxies for symptom severity, and demographic control variables. The results are obtained with ground-measurements and satellite-derived measures of atmospheric particulate matter as well as COVID-19 data from alternative dates. The findings call for further investigation into the association between air pollution and SARS-CoV-2 infection risk. If particulate matter plays a significant role in COVID-19 incidence, it has strong implications for the mitigation strategies required to prevent spreading.
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