生物信息学中记忆效率异构DNA处理的优化模式匹配

Ciprian-Petrisor Pungila, Darius Galis, V. Negru
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引用次数: 1

摘要

我们提出了一种新的、内存高效的方法,通过异构实现和新的架构布局来优化生物信息学中的DNA模式匹配,这比通常的方法有几个优势,我们将详细讨论。我们将我们的方法应用于FASTA开放数据库的DNA序列子集,在不同的硬件设置下,观察到我们的异构实现的显着性能提高。与相同算法的经典实现相比,实际减少了23倍的内存使用,并且具有高通量dna匹配的大规模扩展能力,我们的方法证明了其在可扩展异构架构中的可行性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Optimizing Pattern-Matching for Memory-Efficient Heterogeneous DNA Processing in Bioinformatics
We are proposing a new, memory-efficient approach to optimizing DNA pattern-matching in bioinformatics through a heterogeneous implementation and new architectural layout, that poses several advantages over usual approaches, which we discuss in detail. We are applying our approach on a subset of DNA sequences part of the FASTA open database, under different hardware settings, and observe a significant performance increase in our heterogeneous implementation. With a practical reduction of 23 times less memory usage than a classic implementation of the same algorithm, and massive scaling capabilities for high-throughput DNA-matching, our approach proves its feasibility for scalable heterogeneous architectures.
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