{"title":"生物信息学中记忆效率异构DNA处理的优化模式匹配","authors":"Ciprian-Petrisor Pungila, Darius Galis, V. Negru","doi":"10.1109/SACI.2018.8441000","DOIUrl":null,"url":null,"abstract":"We are proposing a new, memory-efficient approach to optimizing DNA pattern-matching in bioinformatics through a heterogeneous implementation and new architectural layout, that poses several advantages over usual approaches, which we discuss in detail. We are applying our approach on a subset of DNA sequences part of the FASTA open database, under different hardware settings, and observe a significant performance increase in our heterogeneous implementation. With a practical reduction of 23 times less memory usage than a classic implementation of the same algorithm, and massive scaling capabilities for high-throughput DNA-matching, our approach proves its feasibility for scalable heterogeneous architectures.","PeriodicalId":126087,"journal":{"name":"2018 IEEE 12th International Symposium on Applied Computational Intelligence and Informatics (SACI)","volume":"70 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2018-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Optimizing Pattern-Matching for Memory-Efficient Heterogeneous DNA Processing in Bioinformatics\",\"authors\":\"Ciprian-Petrisor Pungila, Darius Galis, V. Negru\",\"doi\":\"10.1109/SACI.2018.8441000\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We are proposing a new, memory-efficient approach to optimizing DNA pattern-matching in bioinformatics through a heterogeneous implementation and new architectural layout, that poses several advantages over usual approaches, which we discuss in detail. We are applying our approach on a subset of DNA sequences part of the FASTA open database, under different hardware settings, and observe a significant performance increase in our heterogeneous implementation. With a practical reduction of 23 times less memory usage than a classic implementation of the same algorithm, and massive scaling capabilities for high-throughput DNA-matching, our approach proves its feasibility for scalable heterogeneous architectures.\",\"PeriodicalId\":126087,\"journal\":{\"name\":\"2018 IEEE 12th International Symposium on Applied Computational Intelligence and Informatics (SACI)\",\"volume\":\"70 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2018 IEEE 12th International Symposium on Applied Computational Intelligence and Informatics (SACI)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/SACI.2018.8441000\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2018 IEEE 12th International Symposium on Applied Computational Intelligence and Informatics (SACI)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/SACI.2018.8441000","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Optimizing Pattern-Matching for Memory-Efficient Heterogeneous DNA Processing in Bioinformatics
We are proposing a new, memory-efficient approach to optimizing DNA pattern-matching in bioinformatics through a heterogeneous implementation and new architectural layout, that poses several advantages over usual approaches, which we discuss in detail. We are applying our approach on a subset of DNA sequences part of the FASTA open database, under different hardware settings, and observe a significant performance increase in our heterogeneous implementation. With a practical reduction of 23 times less memory usage than a classic implementation of the same algorithm, and massive scaling capabilities for high-throughput DNA-matching, our approach proves its feasibility for scalable heterogeneous architectures.