克罗地亚乳腺癌患者创伤后应激障碍症状的患病率、结构和预测因素

Petra, Mara Šimunović, Damir Ljubotina
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引用次数: 1

摘要

背景:乳腺癌是世界范围内女性最常见的癌症。在对疾病的心理反应中,一些患者可能出现创伤后应激障碍(PTSD)症状。本研究的目的是检查克罗地亚乳腺癌患者创伤后应激障碍症状的患病率和结构,并确定这些症状严重程度的一些医学和心理预测因素。研究对象和方法:97名妇女参加了这项研究,她们在完成所有原发性癌症治疗后一个月到六年不等。本研究采用混合方法进行横断面研究。对于PTSD症状的筛查,采用了平民版PTSD检查表(Weathers et al. 1991),并增加了两个开放式问题。结果:采用截断法,21.6%的受试者符合PTSD诊断标准。定性分析表明,对癌症复发的未来导向的侵入性思想,癌症作为压力源的多维性,以及与内部刺激相关的超唤醒症状。在分层多元回归分析中,确定的预测因子占PCL-C评分变异性的35.2%。PTSD严重程度可通过疾病的应激性评估来预测(β=0.45;P <0.001),外部健康控制点(β=0.17;P <0.05)和应对癌症的自我评价(β=-0.17;p < 0.05)。接受根治性乳房切除术的参与者(M=44.41, SD=15.5)的PTSD水平高于部分乳房切除术的参与者(M=33.47, SD=13.68)。结论:考虑到PTSD在一般女性人群中的终生患病率,本研究中获得的PTSD症状患病率应该被认为是有意义的。对乳腺癌后妇女的心理评估应更多地包括创伤后应激反应的评估。此外,研究结果与创伤后应激障碍的基本概念在肿瘤学环境中的应用问题一致,并且可能需要重新定义癌症相关的创伤后应激障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PREVALENCE, STRUCTURE AND PREDICTORS OF POSTTRAUMATIC STRESS DISORDER SYMPTOMS IN CROATIAN PATIENTS FOLLOWING BREAST CANCER
Background: Breast cancer is the most common cancer in female population worldwide. In the psychological response to the disease some patients may develop Posttraumatic Stress Disorder (PTSD) symptomatology. The aim of this study was to examine the prevalence and structure of PTSD symptoms in Croatian patients following breast cancer and to identify some medical and psychological predictors of severity of these symptoms.Subjects and methods: 97 women, who were one month up to six years post-completion of all primary cancer therapy,participated in the study. The present research is cross-sectional with a mixed method approach. For the screening of PTSD symptoms PTSD Checklist - Civilian Version (Weathers et al. 1991) was used, with two open-ended questions added.Results: Using the cutoff method, 21.6 % participants met criteria for PTSD diagnosis. Qualitative analysis indicated future-oriented intrusive thoughts about reoccurrence of cancer, multidimensional nature of cancer as stressors, and hyperarousal symptoms related to internal stimuli. In hierarchical multiple regression analyses, identified predictors accounted for 35.2% of variability in PCL-C score.PTSD severity was predicted by stressfulness appraisal of the disease (β=0.45; p<0.001), external health locus of control (β=0.17; p<0.05) and self-appraisal of coping with cancer (β=-0.17; p<0.05). Participants who underwent radical mastectomy (M=44.41, SD=15.5) showed higher levels of PTSD than participants who had partial mastectomy (M=33.47, SD=13.68).Conclusion: Prevalence of PTSD symptoms obtained in this study should be considered as significant, taking into account the lifetime prevalence of PTSD in the general female population. Psychological assessment of women following breast cancer should more often include an assessment of posttraumatic stress reactions. Furthermore, results are in the line with issues of utilizing basic concept of PTSD in the oncology setting, and possible need of reconceptualization of cancer-related PTSD.
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