Right predilection of lung cancer, does it affect oncologic outcome?

INTRODUCTION: Lung cancer (LC) is the most common malignities and still remain the leading cause of cancer deaths. The aims of this study are to assess the effect of cigarette smoking on the localization and effect of the location of tumors on the prognosis and acute adverse effects. METHODS: 72 patients that given curative thoracic radiotherapy between 24.11.11-14.9.16 in Ankara Atatürk Educational Research Hospital with diagnosed lung cancer were evaluated, retrospectively. Patients diagnosed with LC and underwent curative radiotherapy (RT) were included. Primer endpoints are the acute adverse effect and overall survey (OS). RESULTS: Sixty-five patients (%90,3), were male and seven (%9,7) were female. Tumor localization was 62,5% on the right side and 37.5% on the left side. 62.5% of the patients had concurrent chemotherapy. Median follow-up is 2 years. While the right lung cancer was significantly higher in patients who smoked in NSCLC than in the left lung (p0,05), this ratio was not significant in SCLC (p0,5). There is also an increase in left lung localization with increasing age in all group (p0,2). Acute side effects in NSCLC are more severe in the right lung (p0,043). In the NSCLC group, ARP developed in all 5 patients who smoked more than 50 pct and this ratio is significantly higher than in patients who smoke less than 50 pct year (p0,044). ARP in NSCLC patients is significantly more common in the right lung (p0,05) but there was no significant difference in SCLC (p 0,1). There are no statistically difference in OS between right and left lung cancer. DISCUSSION AND CONCLUSION: LC is often seen in the right lung. Similarly, the acute pulmonary side effects are also more frequently observed on the right side in NSLC. There are no statistically difference in OS between right and left lung cancer.