膳食纤维的降胆固醇作用

S. Ikemoto
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引用次数: 176

摘要

关于几种生理反应的报道越来越多,如降低血浆胆固醇水平、改变血糖反应、改善大肠功能和降低营养物质的可用性。根据最近的证据,大多数分离的水溶性纤维会降低人类和动物的血浆胆固醇。这些包括果胶、车前草和各种胶,如瓜尔胶、刺槐豆胶和改性纤维素,如羧甲基纤维素。食用含有水溶性纤维的富含纤维的食物,如燕麦麸、大麦(ƒÀ-glucan纤维的来源)、豆类和蔬菜,通常会降低血浆胆固醇。在这篇综述中,我将描述两种不同的meta分析和这些作用的一些机制,包括它对胆固醇合成率、VLDL分泌率、LDL周转率和LDL对氧化的敏感性的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cholesterol-lowering Effects of Dietary Fiber
There has been increasing reports concerning several physiological responses, such as lowering of plasma cholesterol levels, modification of glycemic response, improving large bowel function, and lowering nutrients availability. According to recent evidences, most isolated fibers that are water soluble will lower plasma cholesterol in humans and animals. These include pectins, psyllium, and various gums such as guar gum, locust bean gum and modified celluloses such as carboxymethylcellulose. Consumption of fiber-rich sources containing water-soluble fibers, such as oat bran, barley (sources of ƒÀ-glucan fiber), legumes, and vegetables, usually results in a lowering plasma cholesterol. In this review, I will describe two different meta-analysises and some mechanisms of these action including its effects on cholesterol synthesis rates, VLDL secretion rates, LDL turnover rates and susceptibility of LDL to oxidation.
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