生物活性化合物的纳米递送系统

I. Khan, A. Haque, Saghir Ahmad
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引用次数: 2

摘要

科学界正在寻找、发现和发明有利于人类福祉的东西,以寻求对各自问题的可持续解决方案。在与人的生命有关的诸多因素中,人的健康是人们最关心的问题。每个国家都在研究和发展方面投入大量资金,以改善人类健康。食物除了含有适量的营养物质外,最重要的是营养物质的生物利用度。富含天然抗氧化剂但人体无法获取的食物是一种浪费。因此,纳米技术在提高生物活性成分向人体输送系统的效率方面显示出巨大的潜力。本文旨在探讨纳米技术在生物活性化合物输送中的应用,以改善人类健康。今天,制药公司已经开始生产营养保健品来治疗人体的许多异常。营养保健品是一种食品,含有密集的生物活性化合物。这些生物活性化合物有助于对抗多种非传染性疾病,如癌症、糖尿病、骨质疏松症、关节炎和心血管疾病。生物活性化合物的作用取决于其对人体的生物可及性或生物利用度。在这种情况下,纳米技术通过控制1-100纳米尺度的生物活性化合物发挥了至关重要的作用。纳米递送系统的典型例子是脂质体,脂质囊泡,可以在其内部加入各种生物活性化合物。纳米技术的非凡能力正在为可能通过各种方式影响人类生活的新技术铺平道路。纳米技术通过提高生物活性剂的输送效率,可以成为食品医药领域的一项突破性技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nano-delivery system for bioactive compounds
The scientific community is searching, discovering and inventing things for the welfare of humanity in pursuit of sustainable solutions to respective problems. Among the factors relating to human life, human health is the most concerned issue. Each country is investing a significant amount of money in research and development to improve the human health. Besides having appropriate amount of nutrients, the most important aspect of food is the bioavailability of nutrients. Food item rich in natural antioxidants but not accessible to human body is wasteful. Thus, nanotechnology has shown great potential to improve the efficiency of delivery system of bioactive components to the human body. In this article, an effort has been made to discuss the applications of nanotechnology in the delivery of bioactive compounds to improve the human health. Today, the pharmaceutical companies have started the manufacturing of nutraceuticals to treat the number of anomalies in human body. The nutraceuticals are the food, carrying densely packed bioactive compounds. The bioactive compounds help to fight against number of noncommunicable diseases such as cancer, diabetes, osteoporosis, arthritis and cardiovascular diseases. The action of bioactive compounds depends upon the extent of bio accessibility or bioavailability to the human body. In this context, nanotechnology play crucial role by manipulating bioactive compounds in the dimensions of 1-100 nm. The typical example of nano-delivery system is the liposomes, lipid vesicles, can incorporate variety of bioactive compounds in their interior. The exceptional capability of nanotechnology is paving a path of new technologies that may affect the human lives by various means. By improving the delivery efficiency of bioactive agents, nanotechnology can be a breakthrough technology in the world of food medicine.
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