{"title":"芬兰学龄儿童卡介苗再接种规划评价。","authors":"M Tala-Heikkila, T Nurmela, E Tala, J Tuominen","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the need for the BCG revaccination programme of schoolchildren in Finland.</p><p><strong>Design: </strong>Investigating tuberculin sensitivity using the standard WHO Mantoux test and developing a model to estimate the risk of discontinuation, assuming that the annual incidence of tuberculosis within ten years after revaccination will remain at its present level; that the revaccination rate will be 2, 6 or 20%; and that the degree of protection will be 10, 20, 40 or 80%.</p><p><strong>Setting and participants: </strong>Urban and rural schoolchildren--3,346 vaccinated with Copenhagen and 655 with Glaxo BCG vaccine at birth.</p><p><strong>Results of data analysis: </strong>The annual incidence of tuberculosis was 4.2 per 100,000 in the age-group 15-24 years. BCG revaccination was given formerly to 20% of the age cohort but nowadays only 6% or 2% meet the criteria after receiving either Copenhagen or Glaxo BCG at birth. After discontinuation the expected increase of tuberculosis in the age-group 15-24 years is predicted to fall within the limits of 0.1-24 cases per year. If 2% are left without revaccination the increase will be 0.1-2.4 cases.</p><p><strong>Conclusions: </strong>Due to the low annual incidence of tuberculosis in adolescents and to the small risk of increase the BCG revaccination programme has been discontinued from 1990 onwards.</p>","PeriodicalId":77502,"journal":{"name":"Bulletin of the International Union against Tuberculosis and Lung Disease","volume":"66 1","pages":"57-9"},"PeriodicalIF":0.0000,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of the BCG revaccination programme of schoolchildren in Finland.\",\"authors\":\"M Tala-Heikkila, T Nurmela, E Tala, J Tuominen\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the need for the BCG revaccination programme of schoolchildren in Finland.</p><p><strong>Design: </strong>Investigating tuberculin sensitivity using the standard WHO Mantoux test and developing a model to estimate the risk of discontinuation, assuming that the annual incidence of tuberculosis within ten years after revaccination will remain at its present level; that the revaccination rate will be 2, 6 or 20%; and that the degree of protection will be 10, 20, 40 or 80%.</p><p><strong>Setting and participants: </strong>Urban and rural schoolchildren--3,346 vaccinated with Copenhagen and 655 with Glaxo BCG vaccine at birth.</p><p><strong>Results of data analysis: </strong>The annual incidence of tuberculosis was 4.2 per 100,000 in the age-group 15-24 years. BCG revaccination was given formerly to 20% of the age cohort but nowadays only 6% or 2% meet the criteria after receiving either Copenhagen or Glaxo BCG at birth. After discontinuation the expected increase of tuberculosis in the age-group 15-24 years is predicted to fall within the limits of 0.1-24 cases per year. If 2% are left without revaccination the increase will be 0.1-2.4 cases.</p><p><strong>Conclusions: </strong>Due to the low annual incidence of tuberculosis in adolescents and to the small risk of increase the BCG revaccination programme has been discontinued from 1990 onwards.</p>\",\"PeriodicalId\":77502,\"journal\":{\"name\":\"Bulletin of the International Union against Tuberculosis and Lung Disease\",\"volume\":\"66 1\",\"pages\":\"57-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of the International Union against Tuberculosis and Lung Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the International Union against Tuberculosis and Lung Disease","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evaluation of the BCG revaccination programme of schoolchildren in Finland.
Objective: To evaluate the need for the BCG revaccination programme of schoolchildren in Finland.
Design: Investigating tuberculin sensitivity using the standard WHO Mantoux test and developing a model to estimate the risk of discontinuation, assuming that the annual incidence of tuberculosis within ten years after revaccination will remain at its present level; that the revaccination rate will be 2, 6 or 20%; and that the degree of protection will be 10, 20, 40 or 80%.
Setting and participants: Urban and rural schoolchildren--3,346 vaccinated with Copenhagen and 655 with Glaxo BCG vaccine at birth.
Results of data analysis: The annual incidence of tuberculosis was 4.2 per 100,000 in the age-group 15-24 years. BCG revaccination was given formerly to 20% of the age cohort but nowadays only 6% or 2% meet the criteria after receiving either Copenhagen or Glaxo BCG at birth. After discontinuation the expected increase of tuberculosis in the age-group 15-24 years is predicted to fall within the limits of 0.1-24 cases per year. If 2% are left without revaccination the increase will be 0.1-2.4 cases.
Conclusions: Due to the low annual incidence of tuberculosis in adolescents and to the small risk of increase the BCG revaccination programme has been discontinued from 1990 onwards.
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