{"title":"整合生理学的数学理论:在海马体药物发现中的应用","authors":"Omar Bennani, P. Chauvet, Jean-Marc Dupont","doi":"10.1109/BICTA.2010.5645287","DOIUrl":null,"url":null,"abstract":"The modeling and the simulation of biological structure needs a united formalism for all parts of a living system. For this purpose the MTIP (Mathematical Theory of Integrative Physiology) has been developed, by Pr Gilbert Chauvet, to offer an integrated description of a living system. In this paper we will present mainly the passage from a mathematical view of a living subsystem (CA1 circuit of the hippocampus) to its computational implementation and the development of the simulator that goes with in the aim to use and validate the MTIP.","PeriodicalId":302619,"journal":{"name":"2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"The Mathematical Theory of Integrative Physiology: Application to hippocampus for drug discovery\",\"authors\":\"Omar Bennani, P. Chauvet, Jean-Marc Dupont\",\"doi\":\"10.1109/BICTA.2010.5645287\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The modeling and the simulation of biological structure needs a united formalism for all parts of a living system. For this purpose the MTIP (Mathematical Theory of Integrative Physiology) has been developed, by Pr Gilbert Chauvet, to offer an integrated description of a living system. In this paper we will present mainly the passage from a mathematical view of a living subsystem (CA1 circuit of the hippocampus) to its computational implementation and the development of the simulator that goes with in the aim to use and validate the MTIP.\",\"PeriodicalId\":302619,\"journal\":{\"name\":\"2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA)\",\"volume\":\"24 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-11-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/BICTA.2010.5645287\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2010 IEEE Fifth International Conference on Bio-Inspired Computing: Theories and Applications (BIC-TA)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/BICTA.2010.5645287","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Mathematical Theory of Integrative Physiology: Application to hippocampus for drug discovery
The modeling and the simulation of biological structure needs a united formalism for all parts of a living system. For this purpose the MTIP (Mathematical Theory of Integrative Physiology) has been developed, by Pr Gilbert Chauvet, to offer an integrated description of a living system. In this paper we will present mainly the passage from a mathematical view of a living subsystem (CA1 circuit of the hippocampus) to its computational implementation and the development of the simulator that goes with in the aim to use and validate the MTIP.