{"title":"香菜对大鼠血浆铅水平及一些血液学指标的影响","authors":"Ps Mlay, S. Balthazary, E. Phiri, N. Lwitiko","doi":"10.4314/TVJ.V25I2.42036","DOIUrl":null,"url":null,"abstract":"Lead toxicity poses a big risk to animal and human health worldwide, yet its therapy remains difficult. We investigated the effect of cilantro on lead concentration in rat plasma. Rats received 0.25 ml of lead acetate intraperitoneally at 1.6 mg/ml daily for 16 days followed by or without treatment with 0.6 g of cilantro/rat/day mixed in daily ration for sixteen days. The rats were then sacrificed and blood samples taken to determine the plasma levels of lead, packed cell volume (PCV), hemoglobin concentration (Hb), red blood cell (RBC) and white blood cell (WBC) counts using standard procedures. Dry matter (DM), crude protein (CP) and crude fiber (CF) of cilantro treated group were determined by proximate analysis. We observed that cilantro leaves had 12, 28.6 and 11.6% DM, CP and CF contents respectively. Lead injection caused an increase (p Keywords : Cilantro, plasma lead, hemoglobin, PCV, blood cell counts Tanzania Vet Journal Vol. 25 (2) 2008: pp. 132-137","PeriodicalId":181497,"journal":{"name":"Tanzania Veterinary Journal","volume":"34 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of cilantro on plasma lead levels and some hematological parameters in rats\",\"authors\":\"Ps Mlay, S. Balthazary, E. Phiri, N. Lwitiko\",\"doi\":\"10.4314/TVJ.V25I2.42036\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Lead toxicity poses a big risk to animal and human health worldwide, yet its therapy remains difficult. We investigated the effect of cilantro on lead concentration in rat plasma. Rats received 0.25 ml of lead acetate intraperitoneally at 1.6 mg/ml daily for 16 days followed by or without treatment with 0.6 g of cilantro/rat/day mixed in daily ration for sixteen days. The rats were then sacrificed and blood samples taken to determine the plasma levels of lead, packed cell volume (PCV), hemoglobin concentration (Hb), red blood cell (RBC) and white blood cell (WBC) counts using standard procedures. Dry matter (DM), crude protein (CP) and crude fiber (CF) of cilantro treated group were determined by proximate analysis. We observed that cilantro leaves had 12, 28.6 and 11.6% DM, CP and CF contents respectively. Lead injection caused an increase (p Keywords : Cilantro, plasma lead, hemoglobin, PCV, blood cell counts Tanzania Vet Journal Vol. 25 (2) 2008: pp. 132-137\",\"PeriodicalId\":181497,\"journal\":{\"name\":\"Tanzania Veterinary Journal\",\"volume\":\"34 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-02-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tanzania Veterinary Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4314/TVJ.V25I2.42036\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tanzania Veterinary Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/TVJ.V25I2.42036","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
铅中毒对全世界的动物和人类健康构成巨大风险,但其治疗仍然很困难。我们研究了香菜对大鼠血浆铅浓度的影响。大鼠以每天1.6 mg/ml的剂量腹腔注射0.25 ml醋酸铅,连续16天,随后或不注射0.6 g香菜/大鼠/天,连续16天。然后处死大鼠并采集血样,使用标准程序测定血浆铅水平、堆积细胞体积(PCV)、血红蛋白浓度(Hb)、红细胞(RBC)和白细胞(WBC)计数。采用近似分析法测定香菜处理组的干物质(DM)、粗蛋白质(CP)和粗纤维(CF)。结果表明,香菜叶片DM、CP和CF含量分别为12.6%、28.6%和11.6%。关键词:香菜,血浆铅,血红蛋白,PCV,血细胞计数坦桑尼亚兽医杂志Vol. 25 (2) 2008: pp. 132-137
Effect of cilantro on plasma lead levels and some hematological parameters in rats
Lead toxicity poses a big risk to animal and human health worldwide, yet its therapy remains difficult. We investigated the effect of cilantro on lead concentration in rat plasma. Rats received 0.25 ml of lead acetate intraperitoneally at 1.6 mg/ml daily for 16 days followed by or without treatment with 0.6 g of cilantro/rat/day mixed in daily ration for sixteen days. The rats were then sacrificed and blood samples taken to determine the plasma levels of lead, packed cell volume (PCV), hemoglobin concentration (Hb), red blood cell (RBC) and white blood cell (WBC) counts using standard procedures. Dry matter (DM), crude protein (CP) and crude fiber (CF) of cilantro treated group were determined by proximate analysis. We observed that cilantro leaves had 12, 28.6 and 11.6% DM, CP and CF contents respectively. Lead injection caused an increase (p Keywords : Cilantro, plasma lead, hemoglobin, PCV, blood cell counts Tanzania Vet Journal Vol. 25 (2) 2008: pp. 132-137