THE EFFECT OF LOW-INTENSITY ELECTROMAGNETIC RADIATION OF EXTREMELY HIGH FREQUENCY ON THE INDICATORS OF TISSUE OXIDATIVE METABOLISM

The paper considers the indicators of tissue oxidative in rats after 10-fold exposure to low-intensity electromagnetic radiation of the millimeter range. The experiment was carried out on 40 mature male rats of the Wistar line weighing 200-220 g, which were kept in a vivarium with a natural light regime. The animals were divided into 2 groups of 20 rats each. The animals in the first group were biological controls and were in normal vivarium conditions, the animals of the second group were exposed to EHF EMR for 10 sessions daily, in the morning. On the 10th day of EHF exposure, tissue fluorescence indicators were recorded by the diagnostic complex “LAZMA MC” (Modification of LAZMA-MC-III, LAZMA, Moscow, Russia). The results of the study showed that rats exposed to 10-fold EHF exposure had an increase in the values of normalized NADH fluorescence amplitudes and an increase in FAD amplitudes by 82.5% (p<0.05) and 42.6% (p<0.05), as well as redox potential - by 36.9% (p<0.05), respectively, compared to with control. These changes indicate that 10-fold exposure to low-intensity EHF EMR causes an increase in the contribution of aerobic metabolism in rats mainly due to oxidative phosphorylation, leads to activation of the respiratory chain. It can be assumed that these changes in oxidative metabolism are determined primarily by the process of adaptation of microcirculatory blood flow to the needs of tissues for nutrients and the removal of metabolites.