抗反流床楔对胃食管反流症状和胃酸反流的影响

Andrea Oliveira Batista, F. Pinto, R. Dantas
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引用次数: 0

摘要

背景与目的:胃食管反流病在人群中很常见,需要长期的药物和非药物治疗。其中一种非药物治疗方法是在患者仰卧位时抬高床头以避免胃食管反流。本研究的目的是评估两个床楔放置在一个平床垫对症状和胃酸反流的影响。患者和方法:将两个床楔放置在一个平坦的床垫上,一个床楔深度为18 cm(5.5°倾角,楔-1),另一个床楔深度为28 cm(8.6°倾角,楔-2),评估对症状和胃食管反流的影响。12例患者采用床楔-1型,25例患者采用床楔-2型。对所有患者进行症状评估,并进行上消化道内窥镜检查和48小时pH监测。pH值在食管下括约肌近端5厘米处连续测量48小时——24小时在床楔上(18厘米或28厘米深)和24小时没有床楔(即在平坦的床垫上),以随机顺序。结果:与平躺床垫相比,两种楔形床均可减少仰卧位胃食管反流症状的发生频率。床楔-2比床楔-1更容易引起夜间不适。pH监测测量值在两个楔形之间没有差异。结论:所测试的床楔减少了症状的频率,但对胃食管酸反流没有影响。28厘米深的楔形物使大多数使用者在仰卧位时感到不适。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of an Anti-Reflux Bed Wedge on Gastro esophageal Reflux Symptoms and Acid Reflux
Background and Aim: Gastro esophageal reflux disease is common in the population, with a long pharmacological and non-pharmacological treatment. One of the non-pharmacological treatments is the elevation of the head of the bed to avoid gastro esophageal reflux when the patients are in the supine position. The objective of this investigation was to evaluate the effects of two bed wedges placed over a flat mattress on symptoms and acid reflux. Patients and Methods: Two bed wedges were placed over a flat mattress, one with 18 cm depth (5.5° inclination, wedge-1) and the other with 28 cm depth (8.6° inclination, wedge-2) and evaluated the effect on symptoms and gastro esophageal reflux. The bed wedge-1 was tested in 12 patients and the bed wedge-2 in 25 patients. All patients were assessed for symptoms, and underwent upper digestive endoscopy and 48-hour pH monitoring. The pH was measured continuously 5 cm proximal to the lower esophageal sphincter for 48 hours – 24 hours on a bed wedge (18 cm or 28 cm depth) and 24 hours without a bed wedge (i.e., on a flat mattress), in a random order. Results: Both bed wedges reduced the frequency of gastro esophageal reflux symptoms in the supine position compared with the flat mattress. Bed wedge-2 caused more discomfort during the night than the wedge-1. The pH monitoring measurements were not different between the two wedges. Conclusions: The bed wedges tested reduced the frequency of symptoms, but had no effect on gastro esophageal acid reflux. The 28 cm-depth wedge caused discomfort in supine position in most its users.
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