患者COVID-19的糖尿病发病率增加严重:文献综述

Lombok Medical Journal Pub Date : 2023-05-29 DOI:10.29303/lmj.v2i1.978

I. Ketut, Wisnuaji Jayawardhana, A. Info

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引用次数: 0

摘要

印度尼西亚语:糖尿病是COVID-19患者中最常见的病例之一。DM的并发症增加了病人COVID-19的严重程度。作者想知道DM的昏迷为何会增加病人COVID-19的严重程度。它使用的方法是收集与主题相关的文献2020-2021年。通过公共搜索引擎和谷歌学者搜索关键词:Severity和COVID-19或2019- ncov或“Coronavirus Disease 2019”和comorama AND“糖尿病”。一些研究表明，患有梅尔皮氏糖尿病的COVID-19患者的病情恶化，导致死亡。高血糖的病毒感染使病毒因受体增加而附着在寄主细胞上。由于T细胞功能干扰，细胞免疫降低，炎症介质增强并引发细胞因子风暴，因此更容易受到ARDS的影响。DM的并发症和病毒感染一起增加了病人的严重程度。关键词:COVID-19，糖尿病，英语严重程度:糖尿病缺损是最常见的COVID-19患者之一。COVID-19患者的姓名增加了。author想知道为什么DM可以增加COVID-19患者的一些需求。使用的方法是2000年到2021年收集文学作品，这与主题有关。文学研究通过搜索公共引擎和谷歌学学，有keyword和coward -19或2019- ncov或“Coronavirus Disease 2019”和comoramais and“糖尿病”。几个研究人员发现，有19名患者患有糖尿病，这导致死亡。病毒感染和高甘油条件使它更容易感染病毒，并增加受体。细胞功能失调。传染病正在增加，引起恶性风暴，所以它们对ARDS是可比较的。用于传播病毒感染的DM的排序延伸到几个病人。COVID-19，糖尿病，Severity

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Komorbid Diabetes Melitus pada Pasien COVID-19 Meningkatkan Keparahan: Sebuah Tinjauan Pustaka

Bahasa Indonesia : Abstrak Diabetes mellitus salah satu komorbid paling banyak pada pasien COVID-19. Komorbid DM meningkatkan keparahan pasien COVID-19. Penulis ingin mengetahui mengapa komorbid DM dapat meningkatkan keparahan pasien COVID-19. Metode yang digunakan adalah mengumpulkan literatur tahun 2020-2021 yang relevan dengan topik. Literatur dicari melalui mesin pencari PubMed dan Google Scholar dengan kata kunci pencarian Severity AND COVID-19 OR 2019-nCov OR "Coronavirus Disease 2019" AND Comorbid AND "Diabetes mellitus". Beberapa penelitian menyatakan bahwa pasien COVID-19 dengan komorbid diabetes mellitus meningkatkan keparahan yang berujung dengan kematian. Infeksi virus dengan kondisi hiperglikemia memudahkan virus menempel ke sel inang akibat meningkatnya reseptor ACE2. Imunitas seluler menurun akibat terganggunya fungsi sel T. Mediator inflamasi meningkat dan menyebakan terjadinya badai sitokin sehingga rentan mengalami ARDS. Komplikasi DM yang timbul bersamaan dengan infeksi virus menambah keparahan pasien. Kata Kunci : COVID-19, Diabetes Mellitus, Keparahan Bahasa Inggris : Abstract Diabetes mellitus is one of the most common comorbidities in COVID-19 patients. Comorbid DM increases the severity of COVID-19 patients. The author wants to know why comorbid DM can increase the severity of COVID-19 patients. The method used is to collect literature for 2020-2021 that is relevant to the topic. Literature was searched through the search engines PubMed and Google Scholar with keywords Severity AND COVID-19 OR 2019-nCov OR "Coronavirus Disease 2019" AND Comorbid AND "Diabetes mellitus". Several studies have shown that COVID-19 patients with comorbid diabetes mellitus have an increased severity that leads to death. Viral infections with hyperglycemic conditions make it easier for the virus to attach to host cells due to increased ACE2 receptors. Cellular immunity decreases due to disruption of T cell function. Inflammatory mediators increase and cause a cytokine storm so that they are susceptible to ARDS. Complications of DM that occur together with viral infection add to the severity of the patient. Keyword : COVID-19, Diabetes Mellitus, Severity

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Lombok Medical Journal

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