毛发镜检查在不同类型脱发中的应用——一项横断面研究

Ranjitha Krishnegowda, S. Pradhan, A. Gosavi, N. Deshmukh
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摘要

背景:脱发是咨询皮肤科医生最常见的原因之一,临床诊断可能变得令人困惑。鉴于患者和医生对非侵入性诊断的倾向,以及非侵入性诊断方式的流行,毛发镜检查已成为一种很有前途的工具。目的:探讨脱发的各种皮肤镜表现。方法:在获得知情同意后,对在三级医疗中心就诊的100例脱发患者进行横断面研究。拍摄了详细的病史和临床照片。根据需要进行相关调查。皮肤镜检查采用illuco IDS- 1100,放大10倍。采用统计学分析:数据分析采用SPSS 22版软件。采用卡方检验、Kolmogorov-Smirnov检验、Shapiro-Wilk检验,p值均< 0.05。Kappa统计用于评估两种模式之间的一致性。结果:总体而言,牛皮毛(65%)和黄点(65%)是所有类型的脱发中最常见的发现。雄激素源性脱发的毛镜检查最常见的表现是毳毛(90.48%);斑秃、牛皮发、感叹号发各占86.67%;在头癣、螺旋状头发和黑点上;在拔毛癖中,头发会散开。盘状红斑狼疮无滤泡开口、脱屑及滤泡周围色素沉着。临床和皮肤镜诊断kappa一致性为0.776(即基本一致)。在15例难辨性脱发中,进一步调查发现皮镜诊断准确7例(46.67%)。结论:毛发镜检查是一种可靠、无创、快速诊断模棱两可的脱发病例的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utility of Trichoscopy in Various Types of Alopecia - A Cross-Sectional Study
Background: Alopecia is one of the most common reasons for consulting dermatologists, and the clinical diagnosis can become confusing. In light of the inclination of patients and doctors toward non-invasive diagnosis, along with the vogue of non-invasive diagnostic modalities, trichoscopy has become a promising tool. Objectives: To study various dermoscopic patterns of alopecia. Methods: After obtaining informed consent, this cross-sectional study was conducted among 100 patients with alopecia attending a tertiary health care center. A detailed history and clinical photographs were taken. Relevant investigations were done whenever indicated. Dermoscopy was done using illuco IDS- 1100 with 10x magnification. Statistical analysis used: Data was analyzed using SPSS 22 version software. The chi-square test, Kolmogorov-Smirnov test, and Shapiro-Wilk test was used for assessment with a significant P-value of < 0.05. Kappa statistics were used to assess agreement between the two modalities. Results: Overall, vellus hair (65%) and yellow dots (65%) were the most common findings among all types of alopecia. The most common findings on trichoscopy in androgenetic alopecia were vellus hair (90.48%); in alopecia areata, vellus hair, and exclamation mark hair (86.67% each); in tinea capitis, corkscrew hair, and black dots; and in trichotillomania, splaying of hair. Discoid Lupus erythematosus had absent follicular opening, scaling, and perifollicular pigmentation. Clinical and dermoscopic diagnoses were significantly associated with a kappa agreement of 0.776 (i.e., substantial agreement). Out of 15 cases of difficult-to-diagnose alopecia, further investigations showed that dermoscopic diagnosis was accurate in 7 cases (46.67%). Conclusions: Trichoscopy is a reliable, non-invasive, and faster method of diagnosis in ambiguous cases of alopecia.
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