慢性血液透析患者的生存结局:一项在Dakahlia省的埃及研究

H. Yousif, Adel El-Bastawisy, A. Eldeeb
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引用次数: 0

摘要

背景几项研究旨在解释血液透析(HD)患者的高死亡率。我们的研究旨在描述我们省(达喀利亚省)的死亡率,并探讨其潜在的危险因素。这项前瞻性(随访)研究在四个HD单位对120名患者进行了为期12个月的随访(2018年9月至2019年8月)。在入组时和每3个月对所有患者进行12个月的病史记录、体格检查和实验室检查,直至患者死亡。结果120例HD患者中男性72例(60%),女性48例(40%),中位年龄46.5岁。随访1年,26例(21.7%)患者死亡。Log-rank检验的生存分析显示,基于检查的变量(性别、糖尿病、高血压、当前吸烟和主观总体评估),生存时间没有统计学上的显著差异。Cox比例风险模型[评估性别、年龄、糖尿病、高血压、当前吸烟、HD病程(年)和主观全局评估作为HD患者1年死亡率的预测因子]的结果显示,在这7个预测变量中,只有糖尿病是具有统计学意义的独立预测因子。结论Dakahlia省hd相关死亡率较高(21.7%)。糖尿病是死亡的独立危险因素,危险比为2.97。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Survival outcome in patients undergoing chronic hemodialysis: an Egyptian study at Dakahlia Governorate
Background Several research studies aimed to explain the high mortality among hemodialysis (HD) patients. Our study aimed to describe the mortality in our Governorate (Dakahlia) and to explore its potential risk factors. Patients and methods This prospective (follow-up) study was conducted in four HD units on 120 patients who were followed up over the 12-month period (September 2018–August 2019). At enrollment and every 3 months, all patients were subjected to history taking, physical examination, and laboratory tests for the 12-month period or until the patient died. Results The 120 HD cases were 72 (60%) male patients, and 48 (40%) female patients with a median age of 46.5 years. Over 1-year follow-up, 26 (21.7%) patients died. Survival analysis with the Log-rank test shows no statistically significant difference in survival times based on examined variables (sex, diabetes, hypertension, current smoking, and Subjective Global Assessment). The results of the Cox proportional hazards model [to assess sex, age, diabetes, hypertension, current smoking, HD duration (years), and Subjective Global Assessment as predictors of 1-year mortality in HD patients] show that out of these seven predictor variables, only diabetes was a statistically significant independent predictor. Conclusion HD-related mortality is high in Dakahlia Governorate (21.7%). Diabetes mellitus is an independent risk factor for mortality with a hazard ratio of 2.97.
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