A review of neurosurgical manifestations related to COVID-19

to resolve epidemics. During the coronavirus disease 2019 (COVID-19) pandemic, millions of people have suffered from this viral disease. Although COVID-19 is primarily a respiratory infection, neurological symptoms have appeared in many patients. The symptoms and sequelae of nervous system invasion by severe acute respiratory syndrome (SARS)-CoV-2, the causative agent of COVID-19, must be thoroughly investigated and dealt with. Although no studies have analyzed the effects of the Spanish influenza on the nervous system, research has been conducted on nervous system involvement in previous outbreaks of coronaviruses, including SARS and Middle East respiratory syndrome (MERS). The route of virus invasion, the mechanism of damage to the nervous system, the occurrence of symptoms, and sequelae have been studied. SARS-CoV-2 invades the nervous system in a similar way and causes symptoms. Several research papers on this topic are reviewed herein.