扩张型心肌病对心脏行为影响的建模

2018 9th Cairo International Biomedical Engineering Conference (CIBEC) Pub Date : 2018-12-01 DOI:10.1109/CIBEC.2018.8641792

F. H. Mohammed, Essam M. Shafei, A. El-Garhy, M. El-dosoky

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引用次数: 1

摘要

本文建立了左心衰竭的非线性时变集总参数数学模型。扩张型心肌病是收缩期心力衰竭的病因之一。我们做了很多尝试，以确定模型中合适的参数来表达扩张型心肌病作为心力衰竭的情况。心室弹性是诊断扩张型心肌病最合适的指标。在心室弹性降低的情况下，得出了心率和左心室压随时间变化的数学方程。模拟扩张型心肌病对心率、左室压-容积环(P-V环)、左室压、卒中容积和射血分数的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Modeling of the Effect of Dilated Cardiomyopathy on the Behavior of the Heart

In this study, a nonlinear time-varying lumped parameter mathematical model of left sided heart failure had been proposed. One of the causes of systolic heart failure is Dilated Cardiomyopathy, was studied. Many tries were done to know the appropriate parameters in the model to express Dilated Cardiomyopathy as a case of heart failure. Ventricular elastance was found to be the most suitable parameter to present Dilated Cardiomyopathy. Mathematical equations for the change of heart rate and left ventricular pressure with time with decreasing ventricular elastance were concluded. The effects of Dilated Cardiomyopathy on heart rate, left ventricular pressure-volume loop (P-V loop), left ventricular pressure, stroke volume and ejection fraction were modeled.

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2018 9th Cairo International Biomedical Engineering Conference (CIBEC)

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