[丹参对家兔血管紧张素II和心房利钠肽的影响]。

J Z Wang, M E Chen, Y Q Xu
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引用次数: 0

摘要

血管紧张素II (AII)和心房利钠肽(ANP)都与血管功能有关,但作用不同。用放射免疫法观察了丹参对家兔AII和ANP活性的影响。结果发现,与对照组相比,SMC组血浆中AII和ANP浓度显著降低(P < 0.05),脑和心房中AII和ANP浓度略低于对照组(P > 0.05)。提示SMC对血管的作用与AII和ANP的变化有关,脑和血浆中肽变化的差异可能与血脑屏障有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Effect of Salvia miltiorrhiza co. on angiotensin II and atrial natriuretic polypeptide in rabbits].

Both angiotensin II (AII) and atrial natriuretic polypeptide (ANP) are related to the function of blood vessels, but differ in their actions. The authors observed the effect of Salvia miltiorrhiza Co. (SMC) on the activities of AII and ANP in rabbits by radioimmunoassay. It was found that the concentration of AII and ANP in plasma were significantly lower (P less than 0.05), and slightly lower in brain and atrial (P greater than 0.05) in SMC group than in control group. It indicated that the effect of SMC on blood vessels is related to changes of AII and ANP, and that the difference of peptide changes in brain and plasma might be due to the blood-brain barrier.

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